The major highways in the city are U.S. Route 67, which curves along its western edge, and Missouri State Highway 32, which generally runs through it as Karsch Boulevard from northwest to southeast. Much of Farmington's more recent growth has been to the west and northwest, as more businesses try to take advantage of the traffic on U.S. 67. | The major highways in the city are U.S. Route 67, which curves along its western edge, and Missouri State Highway 32, which generally runs through it as Karsch Boulevard from northwest to southeast. Much of Farmington's more recent growth has been to the west and northwest, as more businesses try to take advantage of the traffic on U.S. 67. |