Prion misfolding can be triggered by [[nanoplastics]]. They can cross the blood-brain barrier and interact with proteins. Nanoplastics are prone to interact with proteins, and this interaction fundamentally changes the crucial secondary structure of these biomolecules. This combined with a tertiary misfolding causes [[PrP]]c to misfold into PrPSc, and cause a [[transmissible spongiform encephalopathy]] disease.
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Prion misfolding can be triggered by [[nanoplastics]]. They can cross the blood-brain barrier and interact with proteins. Nanoplastics are prone to interact with proteins, and this interaction fundamentally changes the crucial secondary structure of these biomolecules. This combined with a sporadic tertiary misfolding causes [[PrP]]c to misfold into PrPSc, and cause a [[transmissible spongiform encephalopathy]] disease.