Changes

As of November 19, 2020, "A [[World Health Organization]] panel is now recommending against the use of the antiviral remdesivir in hospitalized Covid-19 patients, saying there is no evidence that the drug — which U.S. regulators have approved for the treatment of the coronavirus — improves mortality."<ref>https://www.statnews.com/2020/11/19/who-recommends-against-remdesivir-covid-19/</ref>

As of November 19, 2020, "A [[World Health Organization]] panel is now recommending against the use of the antiviral remdesivir in hospitalized Covid-19 patients, saying there is no evidence that the drug — which U.S. regulators have approved for the treatment of the coronavirus — improves mortality."<ref>https://www.statnews.com/2020/11/19/who-recommends-against-remdesivir-covid-19/</ref>

Remdesivir depends on a very specific enzyme and thus might not work if its conformation is slightly changed. The overall costs, including hospital expenses, for administering remdesivir to a patient can be as high as $20,000 for a full treatment.

Remdesivir depends on a very specific enzyme and thus might not work if its conformation is slightly changed. The overall costs, including hospital expenses, for administering remdesivir to a patient can be as high as $20,000 for a full treatment. But hospitals receive special financial incentives to administer remdesivir despite its ineffectiveness.<ref>"CMS in October announced interim add-on payments for COVID-19 treatments including remdesivir through the HHS-declared public health emergency. The declaration next expires in January, though stakeholders think it’s likely the emergency will be renewed." [https://medlancr.com/gilead-applied-for-hospital-add-on-payment-for-remdesivir/]</ref>

In contrast, the superior and much less expensive [[hydroxychloroquine]] changes milieu in the cell and makes the [[pH]] unfavorable, such that [[mutations]] are not likely to render HCQ ineffective.

In contrast, the superior and much less expensive [[hydroxychloroquine]] changes milieu in the cell and makes the [[pH]] unfavorable, such that [[mutations]] are not likely to render HCQ ineffective.