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It was McCarthy's charges of Communist infiltration of the State Department that shot him into prominence in 1950. On February 9th speech in Wheeling, [[West Virginia]] at the Colonnade Room of the McClure Hotel he stated:  

It was McCarthy's charges of Communist infiltration of the State Department that shot him into prominence in 1950. On February 9th speech in Wheeling, [[West Virginia]] at the Colonnade Room of the McClure Hotel he stated:  

:''“And ladies and gentlemen, while I cannot take the time to name all the men in the State Department who have been named as active members of the Communist Party and members of a spy ring, I have here in my hand a list of 205 – a list of names that were made known to the Secretary of State as being members of the Communist Party and who nevertheless are still working and shaping policy in the State Department.”'' <ref>The Life and Times of Joe McCarthy: A Biography, Thomas C. Reeves, pg 224." </ref>

{{Cquote|And ladies and gentlemen, while I cannot take the time to name all the men in the State Department who have been named as active members of the Communist Party and members of a spy ring, I have here in my hand a list of 205 – a list of names that were made known to the Secretary of State as being members of the Communist Party and who nevertheless are still working and shaping policy in the State Department.”'' <ref>The Life and Times of Joe McCarthy: A Biography, Thomas C. Reeves, pg 224." </ref>}}

McCarthy compiled a list of 57 security risks and publicly named Robert Service, Gustavo Duran, [[Mary Jane Keeney]] and Harlow Shapley as being on the list. <ref>The Life and Times of Joe McCarthy: A Biography, Thomas C. Reeves, pgs 222-238. </ref>  These names came from the "Lee List" of unresolved State Department security cases compiled by the earlier investigators for the House Appropriates Committee in 1947.  Robert E. Lee was the committee’s lead investigator and supervised preparation of the list.  <ref>U.S. Senate Committee on Foreign Relations, State Department Employee Loyalty Investigations (Washington, D.C.: U.S. Govt. Print. Off., 1950). </ref>

McCarthy compiled a list of 57 security risks and publicly named Robert Service, Gustavo Duran, [[Mary Jane Keeney]] and Harlow Shapley as being on the list. <ref>The Life and Times of Joe McCarthy: A Biography, Thomas C. Reeves, pgs 222-238. </ref>  These names came from the "Lee List" of unresolved State Department security cases compiled by the earlier investigators for the House Appropriates Committee in 1947.  Robert E. Lee was the committee’s lead investigator and supervised preparation of the list.  <ref>U.S. Senate Committee on Foreign Relations, State Department Employee Loyalty Investigations (Washington, D.C.: U.S. Govt. Print. Off., 1950). </ref>