The [[Holy of Holies]] was the term referring to the innermost room of the [[Tabernacle]] and later the Temple. It was in the [[Holy]] of Holies that [[Yahweh]] dwelt.
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In the sack of [[Jerusalem]] by [[Pompey|Pompey Magnus]], Pompey entered and defiled the site as it was in the [[Second Temple]], as described in Flavius Josephus' account of the battle.