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Miller-Urey experiment (view source)
Revision as of 14:46, September 2, 2025
, 14:46, September 2, 2025no edit summary
Miller had performed other experiments between 1952-1954 using two other apparatuses. A few vials of the samples he made were found in the 2000s and analyzed using modern techniques that have more sensitivity.<ref name="Bada2016">Bada, J. L. (2016). One of the foremost experiments of the 20th century: Stanley Miller and the origin of prebiotic chemistry. Metode Science Studies Journal, (6), 183–189. https://doi.org/10.7203/metode.6.4994</ref><ref name="Bada2013">Bada JL. [https://web.archive.org/web/20190225141103id_/http://pdfs.semanticscholar.org/6f46/3e8a3611fa7f25c143991dfddac49c396b73.pdf New insights into prebiotic chemistry from Stanley Miller's spark discharge experiments]. Chem Soc Rev. 2013 Mar 7;42(5):2186-96. doi: 10.1039/c3cs35433d</ref> After modern analysis of his 1950s samples (including the 1953 experiment and volcano experiment), 31 amino acids, 6 amines, and 12 dipeptides/cyclodipeptides formed in very small amounts.<ref name="Bada2016" />
Miller had performed other experiments between 1952-1954 using two other apparatuses. A few vials of the samples he made were found in the 2000s and analyzed using modern techniques that have more sensitivity.<ref name="Bada2016">Bada, J. L. (2016). One of the foremost experiments of the 20th century: Stanley Miller and the origin of prebiotic chemistry. Metode Science Studies Journal, (6), 183–189. https://doi.org/10.7203/metode.6.4994</ref><ref name="Bada2013">Bada JL. [https://web.archive.org/web/20190225141103id_/http://pdfs.semanticscholar.org/6f46/3e8a3611fa7f25c143991dfddac49c396b73.pdf New insights into prebiotic chemistry from Stanley Miller's spark discharge experiments]. Chem Soc Rev. 2013 Mar 7;42(5):2186-96. doi: 10.1039/c3cs35433d</ref> After modern analysis of his 1950s samples (including the 1953 experiment and volcano experiment), 31 amino acids, 6 amines, and 12 dipeptides/cyclodipeptides formed in very small amounts.<ref name="Bada2016" />
''NOTE: moles in Table are relative to glycine = 1 mol [where 4.8 mg was the amount of glycine synthesized]''
{| class="wikitable" style="text-align:left"
{| class="wikitable" style="text-align:left"
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! Amino Acid !! Miller-Urey Experiment 1953 !! Bada 2016 Re-evaluation of 1953 samples
! Amino Acid !! Miller-Urey Experiment 1953 !! Bada 2016 Re-evaluation of 1953 samples
(''moles'' relative to glycine = 1 [where 4.8 mg was the amount of glycine synthesized])
(moles)
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| glycine || Detected || 1.0
| glycine || Detected || 1.0