* When a new product or approach is being studied, it is not usually known whether it will be helpful, harmful, or no different than available alternatives (including no intervention). ... For example, investigators may give a drug or treatment to participants who have high blood pressure to see whether their blood pressure decreases. | * When a new product or approach is being studied, it is not usually known whether it will be helpful, harmful, or no different than available alternatives (including no intervention). ... For example, investigators may give a drug or treatment to participants who have high blood pressure to see whether their blood pressure decreases. |