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'''Sickle cell disease''' is a blood condition seen most commonly in people of [[Africa]]n ancestry. The disorder is caused by a single base pair change in one of the genes that codes for hemoglobin, the blood protein that carries oxygen. This mutation causes the red blood cells to take on a sickle shape, rather than their characteristic donut shape. Individuals who suffer from sickle cell disease are chronically anemic and experience significant damage to their heart, lungs, and kidneys.

'''Sickle cell disease''' is a genetic blood disease seen most commonly in people of [[Africa]]n ancestry. The disorder is caused by a single base pair change in one of the [[gene]]s that codes for [[hemoglobin]], the blood protein that carries oxygen. This mutation causes the red blood cells to take on a sickle shape, rather than their characteristic donut shape. Individuals who suffer from sickle cell disease are chronically anemic and experience significant damage to their heart, lungs, and kidneys.

== Sources ==

== Sources ==

http://www.genome.gov/glossary.cfm?key=sickle%20cell%20disease

http://www.genome.gov/glossary.cfm?key=sickle%20cell%20disease