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Universal common ancestry (view source)
Revision as of 16:37, September 18, 2007
, 16:37, September 18, 2007→Shared endogenous retroviruses
=== Shared endogenous retroviruses ===
=== Shared endogenous retroviruses ===
A [[Retrovirus]] is a virus that incorporates itself into an host cell's DNA, and programs the host cell to produce copies of the cell. [[Endogenous retrovirus]]es (ERVs) are retroviruses that infected an organism's [[germ cell]]s, and were thus passed to the next generation, and incorporated into the organism's genetic line over time.
A [[Retrovirus]] is a virus that incorporates itself into an host cell's DNA, and programs the host cell to produce copies of the virus. [[Endogenous retrovirus]]es (ERVs) are retroviruses that infected an organism's [[germ cell]]s, and were thus passed to the next generation, and incorporated into the organism's genetic line over time.
Researchers estimate that 1% of the human genome is occupied by ERVs, constituting approximately 30,000 different ERVs.<ref>Sverdlov, E. D. (2000) "Retroviruses and primate evolution." BioEssays 22: 161-171. [http://www.ncbi.nlm.nih.gov/sites/entrez?cmd=Retrieve&db=PubMed&list_uids=10655035&dopt=AbstractPlus]</ref> Some of these ERVs are shared by humans and apes, and are found in the same place in the respective genomes. <ref>Lebedev, Y. B., Belonovitch, O. S., Zybrova, N. V, Khil, P. P., Kurdyukov, S. G., Vinogradova, T. V., Hunsmann, G., and Sverdlov, E. D. (2000) "Differences in HERV-K LTR insertions in orthologous loci of humans and great apes." Gene 247: 265-277.[http://www.ncbi.nlm.nih.gov/sites/entrez?cmd=Retrieve&db=PubMed&list_uids=10773466&dopt=AbstractPlus]</ref>
Researchers estimate that 1% of the human genome is occupied by ERVs, constituting approximately 30,000 different ERVs.<ref>Sverdlov, E. D. (2000) "Retroviruses and primate evolution." BioEssays 22: 161-171. [http://www.ncbi.nlm.nih.gov/sites/entrez?cmd=Retrieve&db=PubMed&list_uids=10655035&dopt=AbstractPlus]</ref> Some of these ERVs are shared by humans and apes, and are found in the same place in the respective genomes. <ref>Lebedev, Y. B., Belonovitch, O. S., Zybrova, N. V, Khil, P. P., Kurdyukov, S. G., Vinogradova, T. V., Hunsmann, G., and Sverdlov, E. D. (2000) "Differences in HERV-K LTR insertions in orthologous loci of humans and great apes." Gene 247: 265-277.[http://www.ncbi.nlm.nih.gov/sites/entrez?cmd=Retrieve&db=PubMed&list_uids=10773466&dopt=AbstractPlus]</ref>