| | Most of the body's serotonin is found within the gastrointestinal tract (roughly 90%) and is secreted from enterochromaffin cells. The source of serotonin within the central nervous system is the Raphe Nuclei in the brainstem. It is posited that individuals deficient in serotonin are vulnerable to disorders such as clinical [[depression]], [[Obsessive-Compulsive Disorder]], [[anxiety|anxiety disorders]], [[bipolar disorder]], [[irritable bowel syndrome]], ear infections, and [[migraine]]s. Consequently, medications that increase serotonergic activity in the brain are often used to treat these disorders. Examples include antidepressants such as [[monoamine oxidase inhibitors]] (MAOIs), [[Tricyclic anti-depressants]], and [[Selective-Serotonin-Reuptake-Inhibitors]] (SSRIs). | | Most of the body's serotonin is found within the gastrointestinal tract (roughly 90%) and is secreted from enterochromaffin cells. The source of serotonin within the central nervous system is the Raphe Nuclei in the brainstem. It is posited that individuals deficient in serotonin are vulnerable to disorders such as clinical [[depression]], [[Obsessive-Compulsive Disorder]], [[anxiety|anxiety disorders]], [[bipolar disorder]], [[irritable bowel syndrome]], ear infections, and [[migraine]]s. Consequently, medications that increase serotonergic activity in the brain are often used to treat these disorders. Examples include antidepressants such as [[monoamine oxidase inhibitors]] (MAOIs), [[Tricyclic anti-depressants]], and [[Selective-Serotonin-Reuptake-Inhibitors]] (SSRIs). |