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'''Mitral regurgitation''' is the disease affecting the valves of the heart where there is leaking of blood from the left ventricle back into the left atrium. This can occur as result of [[rheumatic heart disease]], [[myocardial infarction]], [[mitral valve prolapse syndrome]], [[infective endocarditis]] etc. The diagnosis is made by [[echocardiography]]. Other investigations include [[ECG]], chest X-ray and [[cardiac catheterisation]]