| | Drug resistance also arises in viruses. For example, the anti-flu drug Oseltamivir (Tamiflu) was only introduced in the year 2000, and did not receive widespread use until 2004; yet in 2007, type B influenza infections resistant to the drug were observed in Japan.<ref>Johnson, Carla K (2007), "Strain of flu shows resistance to drugs; Findings in Japan trouble scientists", Associated Press, ''The Boston Globe,'' April 4, 2007</ref> | | Drug resistance also arises in viruses. For example, the anti-flu drug Oseltamivir (Tamiflu) was only introduced in the year 2000, and did not receive widespread use until 2004; yet in 2007, type B influenza infections resistant to the drug were observed in Japan.<ref>Johnson, Carla K (2007), "Strain of flu shows resistance to drugs; Findings in Japan trouble scientists", Associated Press, ''The Boston Globe,'' April 4, 2007</ref> |