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| | ::::: The raw data have to already be in a form that allows collaborative work, so I don't see that as much of an obstacle.--[[User:Aschlafly|Aschlafly]] 16:47, 19 June 2008 (EDT) | | ::::: The raw data have to already be in a form that allows collaborative work, so I don't see that as much of an obstacle.--[[User:Aschlafly|Aschlafly]] 16:47, 19 June 2008 (EDT) |
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| | + | [unidenting] You did not really respond to my points. I asked whether, according to your understanding, peer reviewers are normally shown raw data. I said my understanding was they were not. You say "data should be made available..." Is that your opinion, or are you describing actual practice? Second, the usable data is in the paper, as far as I can tell. The graphs do not permit knowing exact value, but you do not seem to be asking for the exact figures used to generate the graph. Look at, for example, figure 1: X axis is generation, Y axis is Optical Density. The caption says: |
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| | + | : Population expansion during evolution of the Cit+ phenotype. Samples frozen at various times in the history of population Ara-3 were revived, and three DM25 cultures were established for each generation. Optical density (OD) at 420 nm was measured for each culture at 24 h. Error bars show the range of three values measured for each generation. |
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| | + | The graph shows a dramatic rise around generation 33000, from less than 0.05 to about .25. What additional data would you like? There are presumably lab books with 33000+ OD measurements (or some multiple of that) but in what sense is the data not available? What exactly regarding this graph would you like to see? |
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| | + | Finally, in the second letter you talk about instances where it is noted that data is not shown. I found 3 such instances: |
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| | + | : page 3 Also, growth on citrate is inhibited by the citrate analog 5-fluorocitrate (data not shown), as was observed for the one previously reported Cit� mutant of E. coli (42, 43). |
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| | + | : page 3 After depleting the glucose in DM25, the earliest Cit+ clones grow almost imperceptibly, if at all, for many hours before they begin efficiently using the citrate (data not shown), whereas later Cit+ cones switch to growth on citrate almost immediately (Fig. 2). |
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| | + | : page 6 These differences were also evident when we monitored the intraday dynamics of mixtures of Cit+ and Cit- cells (data not shown). |
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| | + | In no case do the data seem relevant to the main point of the paper (in the first case, there may be data in the references; in the second case, he is simply noting that early clones grow slowly, but the point is later clones grow fast, for which data are shown; and the third case -- discussing utilization of glucose -- is again tangential to the main conclusion). Why are you interested in these data? -divaricatum 14:21 June 19, 2008 (PDT) |