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Reply to Argon
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::::With regard to 'competent scientists' consider that Behe, in his discussions on this topic has not argued about the 'mechanics' and data presented in Lenski's paper. In his review that can be found on the amazon.com website, he calls Lenksi's work 'fascinating' (and means it in a good way).--[[User:Argon|Argon]] 21:29, 26 June 2008 (EDT)
 
::::With regard to 'competent scientists' consider that Behe, in his discussions on this topic has not argued about the 'mechanics' and data presented in Lenski's paper. In his review that can be found on the amazon.com website, he calls Lenksi's work 'fascinating' (and means it in a good way).--[[User:Argon|Argon]] 21:29, 26 June 2008 (EDT)
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That was strange -- for several hours I was not able to post here,  but now I can.    Here is my response to Argon's comment of 21:16, 26 June 2008 (EDT)
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Argon said,  "The development of citrate metabolizers wasn't the main intent"
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I didn't ask if Cit+ (citrate-eating E. coli bacteria) evolution was the "main intent" of the experiment -- I only asked if Cit+ evolution was one of the original "goals."    There is a misunderstanding about what the word "goal" means -- a goal does not have to be a sure result.    In searches for the Lost Dutchman Mine and the ivory-billed woodpecker,  finding them are "goals."  A "goal" can be one of many goals,  a secondary goal,  a longshot goal,  or whatever.    And "intent" is not part of the definition of "goal" -- "intent" generally means what one plans to do,  but one cannot plan to achieve an uncertain result.    BTW,  the term "citrate metabolizers" is misleading  because the bacteria already had the ability to metabolize citrate but did not have the ability to pass it through the cell walls. 
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Zachary Blount's following statement in comment #115 under the [http://scienceblogs.com/loom/2008/06/02/a_new_step_in_evolution.php New step in evolution] post on Zimmer's blog indicates that Cit+ evolution was one of the original goals of the experiment:
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''"When Dr. Lenski started, he figured the citrate would provide an opportunity that the populations might or might not figure out a way to exploit, thereby presenting a potential point of divergence between the populations (this is my understanding - I will need to check with him to make certain I understand this properly)."''
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Blount then essentially contradicted his above statement by saying that "the intent of the experiment was never to evolve a Cit+ E. coli variant" (comment #115) and that Cit+ evolution was "not a goal" (comment #122).
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Also, the following factors suggest that Cit+ evolution was an original goal of the experiment:
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(1) Cit+ evolution had been observed once before.    Blount reported in comment #115 under the [http://scienceblogs.com/loom/2008/06/02/a_new_step_in_evolution.php New step in evolution] post on Zimmer's blog,  ''"there has been only one report of a spontaneous Cit+ mutant of E. coli in the past century (Hall, B. 1982. Chromosomal mutation for citrate utilization by Escherichia coli K-12. Journal of Bacteriology, 151: 269 � 273.)"). ''
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(2) I and others assumed that a purpose of the glucose-cycling (giving the bacteria an insufficient glucose supply so as to create alternating glucose feeding and glucose starvation) was to favor Cit+ evolution.  I asked Blount if this was in fact a purpose of the glucose-cycling and he did not answer.  I asked what the purpose of the glucose-cycling was if favoring Cit+ evolution was not the purpose,  and he did not answer.
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Was there a research proposal for this whole experiment that started in 1988,    and if so,  what does that proposal say,  if anything,  about my questions? [[User:LarryFarma|LarryFarma]] 10:24, 27 June 2008 (EDT)
    
== removal of content from this page removes context of Lenski's second reply ==
 
== removal of content from this page removes context of Lenski's second reply ==
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