Siteadmin, Check users, nsTeam1RO, nsTeam1RW, nsTeam1_talkRO, nsTeam1_talkRW, oversight, Administrators
30,650
edits
Changes
Jump to navigation
Jump to search
mLine 1:
Line 1: − {{jargon}}+ − +
no edit summary
'''Sickle cell disease''' is a genetic blood disease seen most commonly in people of [[Africa]]n ancestry. Sufferers are chronically [[anemic]] and experience significant damage to their heart, lungs, and kidneys.
'''Sickle cell disease''' is a genetic blood disease seen most commonly in people of [[Africa]]n ancestry. Sufferers are chronically anemic and experience significant damage to their heart, lungs, and kidneys.
==Cause==
==Cause==
{{jargon}}
The disorder is caused by a single [[base pair]] change in one of the [[gene]]s that [[codes for]] [[hemoglobin]], the [[blood protein]] that carries oxygen. This abnormality causes hemoglobin to be formed improperly, and causes individual hemoglobin proteins to clump together, impairing the [[binding]] of oxygen.
The disorder is caused by a single [[base pair]] change in one of the [[gene]]s that [[codes for]] [[hemoglobin]], the [[blood protein]] that carries oxygen. This abnormality causes hemoglobin to be formed improperly, and causes individual hemoglobin proteins to clump together, impairing the [[binding]] of oxygen.