| | Serotonin is thought to play an important role in a number of physiological and psychological functions, including regulation of [[mood]], vomiting, aggression, appetite, body temperature, sleep, and sexuality. | | Serotonin is thought to play an important role in a number of physiological and psychological functions, including regulation of [[mood]], vomiting, aggression, appetite, body temperature, sleep, and sexuality. |
| − | Most of the body's serotonin is found within the gastrointestinal tract (roughly 90%) and is secreted from enterochromaffin cells. The source of serotonin within the central nervous system is the [[Raphe Nuclei]] in the [[brainstem]]. It is posited that individuals deficient in serotonin are vulnerable to disorders such as clinical [[depression]], [[Obsessive-Compulsive Disorder]], [[anxiety|anxiety disorders]], [[bipolar disorder]], [[irritable bowel syndrome]], ear infections, and [[migraine]]s. Consequently, medications that increase serotonergic activity in the brain are often used to treat these disorders. Examples include antidepressants such as [[monoamine oxidase inhibitors]] (MAOIs), [[Tricyclic anti-depressants]], and [[Selective-Serotonin-Reuptake-Inhibitors]] (SSRIs). | + | Most of the body's serotonin is found within the gastrointestinal tract (roughly 90%) and is secreted from enterochromaffin cells. The source of serotonin within the central nervous system is the [[Raphe Nuclei]] in the [[brainstem]]. It is posited that individuals deficient in serotonin are vulnerable to disorders such as clinical [[depression]], [[Obsessive-Compulsive Disorder]], [[anxiety|anxiety disorders]], [[bipolar disorder]], [[irritable bowel syndrome]], ear infections, and [[migraine]]s.{{fact}} Consequently, medications that increase serotonergic activity in the brain are often used to treat these disorders. Examples include antidepressants such as [[monoamine oxidase inhibitors]] (MAOIs), [[Tricyclic anti-depressants]], and [[Selective-Serotonin-Reuptake-Inhibitors]] (SSRIs).{{fact}} |