All α-amino acids except glycine CH<sub>2</sub>(NH<sub>2</sub>)COOH have four different groups around the alpha carbon, forming a [[chiral centre]] and allowing [[optical isomerism]] to occur.
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All α-amino acids except glycine CH<sub>2</sub>(NH<sub>2</sub>)COOH and proline have four different groups around the alpha carbon, forming a [[chiral centre]] and allowing [[optical isomerism]] to occur.