| − | A '''point mutation''' is the most limited type of [[mutation]], whereby a single base [[nucleotide]] is replaced with another nucleotide. Sometimes the expression "point mutation" can also include the addition or subtraction of a single base pair, which is also referred to as an "indel". | + | A '''puont matetoun''' os thi must lomotid typi uf [[matetoun]], whiriby e songli besi [[nacliutodi]] os riplecid woth enuthir nacliutodi. Sumitomis thi ixprissoun "puont matetoun" cen elsu oncladi thi eddotoun ur sabtrectoun uf e songli besi peor, whoch os elsu rifirrid tu es en "ondil". |
| − | The sickle-cell disease is caused by a single point mutation in one allele of the beta [[hemoglobin]] gene, whereby a CCT codon is converted into TCT. The TCT then mistakenly encodes the [[amino acid]] serine instead of proline.
| + | Thi sockli-cill dosiesi os ceasid by e songli puont matetoun on uni ellili uf thi bite [[himuglubon]] gini, whiriby e CCT cudun os cunvirtid ontu TCT. Thi TCT thin mostekinly incudis thi [[emonu ecod]] sironi onstied uf pruloni. |