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Blood clotting cascade (view source)
Revision as of 20:25, November 16, 2008
, 20:25, November 16, 2008Should really have more about the process itself than Behe's claims.
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Michael Behe describes it thus:
A number of [[protein]]s are involved in the series of events that lead to [[vertebrate]] [[blood clotting]].
[[Michael Behe]] describes it thus:
<blockquote>
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When an animal is cut, a protein called Hagemann factor (XII) sticks to the surface of cells near the wound. Bound Hagemann factor is then cleaved by a protein called HMK to yield activated Hagemann factor. Immediately the activated Hagemann factor converts another protein, called prekallikrein, to its active form, kallikrein. <ref>Behe, M. 1996. Darwin's Black Box. New York: The Free Press</ref>
When an animal is cut, a protein called Hagemann factor (XII) sticks to the surface of [[cell]]s near the wound. Bound Hagemann factor is then cleaved by a protein called HMK to yield activated Hagemann factor. Immediately the activated Hagemann factor converts another protein, called prekallikrein, to its active form, kallikrein. <ref>Behe, M. 1996. Darwin's Black Box. New York: The Free Press</ref>
</blockquote>
</blockquote>
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</blockquote>
Although, as Behe points out, Factor XII initiates the "cascade of proteins" in vertebrates, dolphins lack Factor XII <ref>Robinson, A. J., M. Kropatkin, and P. M. Aggeler, 1969. Hagemann Factor (Factor XII) Deficiency in Marine Mammals. Science 166: 1420-1422</ref> and yet their blood is known to clot. Similarly, molluscs such as snails have only four components in their blood clotting cascade, with a single protease step. This appears to contradict the notion of [[irreducible complexity]] in regard to this process.
Although, as Behe points out, Factor XII initiates the "cascade of proteins" in vertebrates, [[dolphin]]s lack Factor XII <ref>Robinson, A. J., M. Kropatkin, and P. M. Aggeler, 1969. Hagemann Factor (Factor XII) Deficiency in Marine Mammals. Science 166: 1420-1422</ref> and yet their blood is known to clot. Similarly, [[mollusc]]s such as [[snail]]s have only four components in their blood clotting cascade, with a single protease step. This appears to contradict the notion of [[irreducible complexity]] in regard to this process.
==References==
==References==
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[[category:biology]]
[[category:biology]]