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There's a third JE; the 'medium,' Jon Edwards. Don't know if he's worth an article here or not, but it may be worth mentioning that neither of these JEs are him. [[User:Tsumetai|Tsumetai]] 10:17, 14 March 2007 (EDT)
 
There's a third JE; the 'medium,' Jon Edwards. Don't know if he's worth an article here or not, but it may be worth mentioning that neither of these JEs are him. [[User:Tsumetai|Tsumetai]] 10:17, 14 March 2007 (EDT)
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Hi.
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Smallpox vaccination, which involves the administration of attenuated live virus, (and has well-recognized dangers) was not in use at this time. 
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Smallpox itself killed millions...the first successful preventative strategy, other than isolation, was ''innoculation'', which involved taking material from the pox of an ill patient, and injecting it into the skin of a healthy patient.  One of the first successful human trials was done on this, and used actual statistics.  Unfortunately, it was done on prisoners and orphans.  It did, however, provide decent protection, but there was, by today's standards, a very high rate of illness and death (lower than the rate of smallpox, though, during epidemic times).
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Eventually, vaccination was developed, which was actually more of a form of innoculation, as modern genetics had not yet been developed.  An attenuated live virus (of Cowpox, not smallpox) was used.  This had a much lower rate of complications than using smallpox itself, but still could lead to serious illness, especially in young or unhealthy people exposed to the virus, or to those recently vaccinated. 
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I'd be happy to share more, if anyone is interested.
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[[User:Palmd001|Palmd001]] 14:52, 23 March 2007 (EDT)
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