Changes

A '''point mutation''' is the most limited type of [[mutation]], whereby a single base [[nucleotide]] is replaced with another nucleotide.  Sometimes the expression "point mutation" can also include the addition or subtraction of a single base pair, which is also referred to as an "indel".

A '''point mutation''' is the most limited type of [[mutation]], whereby a single base [[nucleotide]] is replaced with another nucleotide.  Sometimes the expression "point mutation" can also include the addition or subtraction of a single base pair, which is also referred to as an "indel".

The sickle-cell disease is caused by a single point mutation in one allele of the beta [[hemoglobin]] gene, whereby a CCT codon is converted into TCT.  The TCT then mistakenly encodes the [[amino acid]] serine instead of proline.

The sickle-cell disease is caused by a single point mutation in one allele of the beta [[hemoglobin]] gene, whereby a CCT codon is converted into TCT.  The TCT then mistakenly encodes the [[amino acid]] serine instead of proline.

A point mutation cannot add new information to the genome. <ref>AIG article [http://www.answersingenesis.org/articles/2008/02/01/feedback-new-information]</ref>

Point mutations do not add new information to the genome. <ref>Purdom, Georgia, [http://www.answersingenesis.org/articles/2008/02/01/feedback-new-information Feedback: Evidence of New Genetic Information?], 1st February, 2009 (Answers in Genesis)</ref>

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