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For example, in 1962 Japan instituted mandatory vaccination against influenza in school children. This continued until 1987 when the program was changed to optional; it was abandoned in 1994. Approximately 85 percent of children were estimated to have been vaccinated.<ref>{{hnb|Glezen|2004}}</ref>  Several studies examined the mortality rates due to influenza during this period of time and revealed that the death rates due to influenza in all population groups was drastically decreased, including older adult populations. Since there was no increased rate of vaccination in these populations, the decreased mortality was caused by herd immunity effects of vaccinating so many children. <ref>http://www.newsrx.com/newsletters/Vaccine-Weekly/2001-04-11/200104113335VW.html Mandatory Vaccination of Japanese Schoolchildren Demonstrates "Herd Immunity" </ref> Many researchers have written that this and other evidence argues strongly for mandatory vaccination programs world wide as a means of controlling many diseases and preventing  a [[pandemic]].<ref> http://www.pubmedcentral.nih.gov/articlerender.fcgi?artid=1360502 Herd Immunity</ref>
 
For example, in 1962 Japan instituted mandatory vaccination against influenza in school children. This continued until 1987 when the program was changed to optional; it was abandoned in 1994. Approximately 85 percent of children were estimated to have been vaccinated.<ref>{{hnb|Glezen|2004}}</ref>  Several studies examined the mortality rates due to influenza during this period of time and revealed that the death rates due to influenza in all population groups was drastically decreased, including older adult populations. Since there was no increased rate of vaccination in these populations, the decreased mortality was caused by herd immunity effects of vaccinating so many children. <ref>http://www.newsrx.com/newsletters/Vaccine-Weekly/2001-04-11/200104113335VW.html Mandatory Vaccination of Japanese Schoolchildren Demonstrates "Herd Immunity" </ref> Many researchers have written that this and other evidence argues strongly for mandatory vaccination programs world wide as a means of controlling many diseases and preventing  a [[pandemic]].<ref> http://www.pubmedcentral.nih.gov/articlerender.fcgi?artid=1360502 Herd Immunity</ref>
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The USA has mandatory vaccination according to an official CDC schedule. Enforcement is left to the states. Most states have medical and religious exemptions. Some states make it very easy to opt out of vaccines, while other states strictly enforce compliance for school attendance. The difference in vaccination rates between these states is actually very slight, and not nearly enough to affect herd immunity.   
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The USA has mandatory vaccination according to an official CDC schedule. Enforcement is left to the states. Most states have medical and religious exemptions. Some states make it very easy to opt out of vaccines, while other states strictly enforce compliance for school attendance. The difference in vaccination rates between these states is actually very slight, and usually not nearly enough to affect herd immunity.   
    
As of February 2008, the CDC noted that "fewer than 100 measles cases are now reported annually in the United States and virtually all of those are linked to imported cases" in which someone is infected during overseas travel.  The USA maintains herd immunity for measles, even in states where it is easy to opt out of vaccination requirements.<ref> [http://www.cdc.gov/mmwr/preview/mmwrhtml/mm5708a3.htm]</ref> Measles can be serious; according to an article in The Times, "About one in every 15 children has complications that can include meningitis, pneumonia, fits, encephalitis (swelling of the brain), blindness and brain damage."<ref>The Sunday Times, ''How the MMR scare led to the return of measles'', February 8, 2009[http://www.timesonline.co.uk/tol/life_and_style/health/article5683687.ece]</ref>  In the England and Wales, there were 1,348 cases of measles in 2008; two children died of the disease. <ref>The Sunday Times, ''MMR doctor Andrew Wakefield fixed data on autism'', by Brian Deer, February 8, 2009 [http://www.timesonline.co.uk/tol/life_and_style/health/article5683671.ece]</ref>
 
As of February 2008, the CDC noted that "fewer than 100 measles cases are now reported annually in the United States and virtually all of those are linked to imported cases" in which someone is infected during overseas travel.  The USA maintains herd immunity for measles, even in states where it is easy to opt out of vaccination requirements.<ref> [http://www.cdc.gov/mmwr/preview/mmwrhtml/mm5708a3.htm]</ref> Measles can be serious; according to an article in The Times, "About one in every 15 children has complications that can include meningitis, pneumonia, fits, encephalitis (swelling of the brain), blindness and brain damage."<ref>The Sunday Times, ''How the MMR scare led to the return of measles'', February 8, 2009[http://www.timesonline.co.uk/tol/life_and_style/health/article5683687.ece]</ref>  In the England and Wales, there were 1,348 cases of measles in 2008; two children died of the disease. <ref>The Sunday Times, ''MMR doctor Andrew Wakefield fixed data on autism'', by Brian Deer, February 8, 2009 [http://www.timesonline.co.uk/tol/life_and_style/health/article5683671.ece]</ref>
    
The CDC notes that when a measles outbreak occurs, the cost to taxpayers can be substantial.  Public health responsibilities include "identification of cases, isolation of patients and vaccination, administration of immune globulin, and voluntary quarantine of contacts who have no evidence of measles immunity...In Iowa, the public health response to one imported measles case cost approximately $150,000."<ref>Centers for Disease Control and Prevention, Morbidity and Mortality Weekly Report, ''Outbreak of Measles --- San Diego, California, January--February 2008'', February 29, 2008 [http://www.cdc.gov/mmwr/preview/mmwrhtml/mm5708a3.htm]</ref>
 
The CDC notes that when a measles outbreak occurs, the cost to taxpayers can be substantial.  Public health responsibilities include "identification of cases, isolation of patients and vaccination, administration of immune globulin, and voluntary quarantine of contacts who have no evidence of measles immunity...In Iowa, the public health response to one imported measles case cost approximately $150,000."<ref>Centers for Disease Control and Prevention, Morbidity and Mortality Weekly Report, ''Outbreak of Measles --- San Diego, California, January--February 2008'', February 29, 2008 [http://www.cdc.gov/mmwr/preview/mmwrhtml/mm5708a3.htm]</ref>
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Other diseases besides the measles have also started not only to reappear but also to kill babies.  Hib (<i>[[Haemophilus influenzae]]</i> type B) recently killed an infant in Minnesota by causing meningitis in the baby.  The child who died had not been vaccinated.  Two others who had been either partially vaccinated, but not fully protected, or had an immune deficiency were seriously sickened.  The vaccine for Hib is less than twenty years old, but this is the first death due to the disease in the state of Minnesota since the vaccine was introduced.<ref>[http://children.webmd.com/vaccines/news/20090123/hib-outbreak-kills-unvaccinated-child Hib Outbreak Kills Unvaccinated Child]</ref>
    
== Adverse Reactions ==
 
== Adverse Reactions ==
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