| − | '''Holoprosencephaly''' is a birth defect where the forebrain does not separate properly into two halves during early fetal life. The disorder results in mild to severe [[brain]] malformation and is sometimes fatal. It may be caused by environmental or genetic factors. Holoprosencephaly affects between 1 in 5,000 and 1 in 10,000 live births. | + | '''Holoprosencephaly''' is a birth defect where the forebrain does not separate properly into two halves during early fetal life. The disorder results in mild to severe [[brain]] [[malformation]] and is sometimes fatal. It may be caused by environmental or genetic factors. Holoprosencephaly affects between 1 in 5,000 and 1 in 10,000 live births. |