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article on chlorpromazine, notably the first antipsychotic
'''Chlorpromazine''', marketed in the US as '''Thorazine''', is a typical antipsychotic drug and was the first antipsychotic to be synthesized, circa December 1950. Despite the drug's age, it still holds a place in the modern treatment of psychosis, though it is now used less often than newer antipsychotics (such as quetiapine).
== Indications ==
Chlorpromazine is indicated for the treatment of:
*Schizophrenia
*Severe mania in people with bipolar disorder
*Uncontrollable hiccups
*As a low-dose and short-term treatment for nausea and vomiting
== Side effects ==
Like most antipsychotics, chlorpromazine has a number of side effects, while most are common, some can be more serious, possibly resulting in [[Death]]. Side effects are:
'''Common'''
*Drowsiness
*Dizziness
*Orthostatic hypotention
*Worsening of symptoms upon stopping treatment with the drug
'''Rare'''
*Neuroleptic malignant syndrome, a potentially deadly condition in which the drug disrupts the body's thermal regulation system, causing high fever and delirium.
*[[Tardive dyskinesia]], a potentially incurable neurologic disorder, usually reported with long-term use.
== Indications ==
Chlorpromazine is indicated for the treatment of:
*Schizophrenia
*Severe mania in people with bipolar disorder
*Uncontrollable hiccups
*As a low-dose and short-term treatment for nausea and vomiting
== Side effects ==
Like most antipsychotics, chlorpromazine has a number of side effects, while most are common, some can be more serious, possibly resulting in [[Death]]. Side effects are:
'''Common'''
*Drowsiness
*Dizziness
*Orthostatic hypotention
*Worsening of symptoms upon stopping treatment with the drug
'''Rare'''
*Neuroleptic malignant syndrome, a potentially deadly condition in which the drug disrupts the body's thermal regulation system, causing high fever and delirium.
*[[Tardive dyskinesia]], a potentially incurable neurologic disorder, usually reported with long-term use.