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'''Ziprasidone''', sold in the US under the brand name '''Geodon''', and also available as a fast-acting intramuscular injection for acute settings, is an atypical [[antipsychotic]] used to treat schizophrenia and mania in [[bipolar disorder]]. Unlike most antipsychotics, when taken orally, ziprasidone must be administered with food or the drug will not be absorbed sufficiently by the small intestine, leading to decreased effect.
== Indications ==
*Schizophrenia
*Bipolar mania
*Mixed states in bipolar disorder
== Side effects ==
Ziprasidone can have many side effects, some common, some rare and life-threatening. Side effects are:
'''Common'''
*Drowsiness
*Sudden drop in blood pressure upon standing
*Dizziness
*Induction of mania in some bipolar patients
*Chest pains
'''Rare'''
*Neuroleptic malignant syndrome
*[[Tardive dyskinesia]]
*Torsades de pointes, a rare heart defect
*Increased risk of death in elderly patients with dementia, for which ziprasidone received a Black Box Warning from the FDA.
== Other uses ==
Some evidence has suggested that ziprasidone may be useful in the treatment of nervous tics in people with such disorders.