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A supplementary type of insecticide are Insect Growth Regulators (IGR’s), such as hydroprene (''Gentrol'') and methoprene, which do not actually kill bedbugs, but instead work to prevent reproduction by disrupting the development of immature bedbugs, resulting in being unable to reproduce. This process takes longer but it can ensure an eventual end of the infestation, if contact with all bedbugs is made, but usually this chemical is used in conjunction with other insecticides.<ref>http://www.bed-bug.org/insectisides-for-bed-bugs/</ref><ref>http://www.zoecon.com/pdfs/GentrolBedBug.pdf</ref>  
 
A supplementary type of insecticide are Insect Growth Regulators (IGR’s), such as hydroprene (''Gentrol'') and methoprene, which do not actually kill bedbugs, but instead work to prevent reproduction by disrupting the development of immature bedbugs, resulting in being unable to reproduce. This process takes longer but it can ensure an eventual end of the infestation, if contact with all bedbugs is made, but usually this chemical is used in conjunction with other insecticides.<ref>http://www.bed-bug.org/insectisides-for-bed-bugs/</ref><ref>http://www.zoecon.com/pdfs/GentrolBedBug.pdf</ref>  
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One report indicates that bed bugs have not shown resistance to a relatively new material, ''chlorfenapyr'' (marketed as ''Phantom'').<ref>http://newyorkvsbedbugs.org/2010/08/12/the-workmanlike-chlorfenapyr</ref> which is a non-repellent, slower but long-lasting residual killer. However, use of chlorfenapyr is only legal for licensed exterminators,<ref>http://store.parsonspestcontrol.com/msds/Phantom_Label.pdf</ref> and may require ten or more days to kill the bugs, during which the insect may still be active and females may wander and deposit viable eggs in other locations. Currently, microencapsulated materials such as contain esfenvalerate (''Onslaught'') or lamba-cyhalothrin (''Demand CS'') may offer the ''rapid'' reduction of susceptible populations.<ref>http://ento.psu.edu/extension/factsheets/bedbugs</ref> Also reported effective against some pyrethroid-resistant bugs were two pyrethroid-based dusts, (''Tempo Dust;'' ''Drione'') as well as diatomaceous earth.<ref>http://newyorkvsbedbugs.org/2009/05/22/finally-researchers-on-the-efficacy-of-dusts/</ref>
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One report indicates that bed bugs have not shown resistance to a relatively new material, ''chlorfenapyr'' (marketed as ''Phantom'').<ref>http://newyorkvsbedbugs.org/2010/08/12/the-workmanlike-chlorfenapyr</ref> which is a non-repellent, slower but virulent long-lasting residual killer.<ref>[http://onlinelibrary.wiley.com/doi/10.1002/ps.2002  Alvaro Romero,
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  Michael F Potter, Kenneth F Haynes, ''Evaluation of chlorfenapyr for control of the bed bug, Cimex lectularius L''], Pest Management, Science</ref>/abstract;jsessionid=0C9A4DABF17CB4DD010C0F263C46D8F3.d01t02 However, use of chlorfenapyr may be only legal for licensed exterminators,<ref>http://store.parsonspestcontrol.com/msds/Phantom_Label.pdf</ref> and may require ten or more days to kill the bugs, during which the insect may still be active and females may wander and deposit viable eggs in other locations. Currently, microencapsulated materials such as contain esfenvalerate (''Onslaught'') or lamba-cyhalothrin (''Demand CS'') may offer the ''rapid'' reduction of susceptible populations.<ref>http://ento.psu.edu/extension/factsheets/bedbugs</ref> Also reported effective against some pyrethroid-resistant bugs were two pyrethroid-based dusts, (''Tempo Dust;'' ''Drione'') as well as diatomaceous earth.<ref>http://newyorkvsbedbugs.org/2009/05/22/finally-researchers-on-the-efficacy-of-dusts/</ref>
    
Possibly the most effective agent against bed begs, with long residual effect, is Propoxur (marketed under the registered trademark name Baygon) a carbamate pesticide with a somewhat murky regulatory history. In a test of its effectiveness against bedbugs, while some of today’s leading pesticides could not kill even half of the bugs, propoxur a well as chlorpyrifos (an organophosphate) killed them all in an hour. However, Propoxur is a neurotoxin,  toxic to humans if ingested, and [[EPA]] research has found human nervous systems could be harmed, with infants and children being in the most danger. Serious overexposure can also cause death by cardiorespiratory depression.<ref>[http://www.faqs.org/periodicals/201006/2054573271.html ''Bed Bugs: The Pesticide Dilemma'']</ref> It is therefore, like chlorpyrifos,<ref>http://www.epa.gov/oppsrrd1/op/chlorpyrifos.htm</ref> banned by the EPA for use in locations where children may be present (residential buildings and hotels). Recently, the EPA denied a request  by the state of Ohio to allow its use therein by licensed exterminators.<ref>http://bedbugger.com/2010/06/11/bed-bugs-cheer-ohios-propoxur-exemption-request-denied/</ref>  
 
Possibly the most effective agent against bed begs, with long residual effect, is Propoxur (marketed under the registered trademark name Baygon) a carbamate pesticide with a somewhat murky regulatory history. In a test of its effectiveness against bedbugs, while some of today’s leading pesticides could not kill even half of the bugs, propoxur a well as chlorpyrifos (an organophosphate) killed them all in an hour. However, Propoxur is a neurotoxin,  toxic to humans if ingested, and [[EPA]] research has found human nervous systems could be harmed, with infants and children being in the most danger. Serious overexposure can also cause death by cardiorespiratory depression.<ref>[http://www.faqs.org/periodicals/201006/2054573271.html ''Bed Bugs: The Pesticide Dilemma'']</ref> It is therefore, like chlorpyrifos,<ref>http://www.epa.gov/oppsrrd1/op/chlorpyrifos.htm</ref> banned by the EPA for use in locations where children may be present (residential buildings and hotels). Recently, the EPA denied a request  by the state of Ohio to allow its use therein by licensed exterminators.<ref>http://bedbugger.com/2010/06/11/bed-bugs-cheer-ohios-propoxur-exemption-request-denied/</ref>  
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