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→Lack of mechanism
# The blood of tunicates such as the sea squirt is based on the rare element [[vanadium]] instead of the abundant [[iron]] used in other vertebrates, which would have required a complete re-tooling of its entire circulatory biochemistry <ref>http://www.earthlife.net/inverts/ascidiacea.html</ref>.
# The blood of tunicates such as the sea squirt is based on the rare element [[vanadium]] instead of the abundant [[iron]] used in other vertebrates, which would have required a complete re-tooling of its entire circulatory biochemistry <ref>http://www.earthlife.net/inverts/ascidiacea.html</ref>.
# Animals exist in isolated places without any plausible motivation or means for getting there, such as on remote islands or more than 1200 feet high on top of the vertical cliffs of [[Devils Tower]]. Even humans (though large and intelligent) were unable to ascend the peak until 1893, and required specialized climbing equipment.
# Animals exist in isolated places without any plausible motivation or means for getting there, such as on remote islands or more than 1200 feet high on top of the vertical cliffs of [[Devils Tower]]. Even humans (though large and intelligent) were unable to ascend the peak until 1893, and required specialized climbing equipment.
# Evolution cannot explain overgrown shrubbery, which originated even before humans were alive to trim it.
===Maladaptation===
===Maladaptation===