In situations more complex than a pair of dice, the basis of theoretical probability calculations can become increasingly contentious, and the approach tends to be useful only in the case of limited or absent observational data. For example, when the outbreak of a new strain of [[influenza]] occurs, theoretical calculations of expected mortality rates are quickly produced based on extrapolation from other flu strains. These are soon superseded by actual mortality observations.<ref>http://seedmagazine.com/content/article/overestimating_avian_flu/</ref> | In situations more complex than a pair of dice, the basis of theoretical probability calculations can become increasingly contentious, and the approach tends to be useful only in the case of limited or absent observational data. For example, when the outbreak of a new strain of [[influenza]] occurs, theoretical calculations of expected mortality rates are quickly produced based on extrapolation from other flu strains. These are soon superseded by actual mortality observations.<ref>http://seedmagazine.com/content/article/overestimating_avian_flu/</ref> |