[[Ronald Reagan]] famously suffered Alzheimer's disease in his later years.
[[Ronald Reagan]] famously suffered Alzheimer's disease in his later years.
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== Alzheimer's disease and obesity ==
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In 2005, WebMD published:
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{{cquote|People with diabetes are at particularly high risk of [[Alzheimer's disease]]. But now there's strong evidence that people with high [[insulin]] levels -- long before they get diabetes -- already are on the road to Alzheimer's disease.
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As the body becomes more and more overweight, it becomes more and more resistant to the blood-sugar-lowering effects of insulin. To counter this insulin resistance, the body keeps making more insulin...
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'''Insulin Triggers Amyloid Buildup'''
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High insulin levels are known to cause [[blood vessel]]s to become inflamed....
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One dangerous effect of this insulin-caused brain inflammation is increased brain levels of beta-amyloid. Beta-amyloid is the twisted protein that's the main ingredient in the sticky plaques that clog the brains of people with Alzheimer's disease.
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"What was striking was the magnitude of the effect," Craft tells WebMD. "Inflammation can be a result of amyloid elevations but can also create an environment in which amyloid is made more readily. Inflammation can be both the result and cause of amyloid production."<ref>[http://www.webmd.com/alzheimers/guide/20061101/obesity-alzheimers-risk Obesity and Alzheimer's: High Insulin Levels Linked to Alzheimer's]</ref>}}