Difference between revisions of "Citric acid cycle"

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(New page: ==Cycle Overview== ===Reactions of the Cycle=== ===Historical Perspective=== ==Metabolic Sources of Acetyl-Coenzyme A== ===Pyruvate Dehydrogenase Multienzyme Complex=== ===Control of Pyruv...)
 
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==Cycle Overview==
 
==Cycle Overview==
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The '''citric acid cycle''' is an ingenious series of reactions that oxidizes the acetyl group of acetyl-CoA to two molecules of CO<sub>2</sub> in a manner that conserves the liberated free energy for utilization in [[ATP]] generation.
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===Reactions of the Cycle===
 
===Reactions of the Cycle===
 
===Historical Perspective===
 
===Historical Perspective===
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==Metabolic Sources of Acetyl-Coenzyme A==
 
==Metabolic Sources of Acetyl-Coenzyme A==
 
===Pyruvate Dehydrogenase Multienzyme Complex===
 
===Pyruvate Dehydrogenase Multienzyme Complex===

Revision as of 13:59, January 31, 2008

Cycle Overview

The citric acid cycle is an ingenious series of reactions that oxidizes the acetyl group of acetyl-CoA to two molecules of CO2 in a manner that conserves the liberated free energy for utilization in ATP generation.

Reactions of the Cycle

Historical Perspective

Metabolic Sources of Acetyl-Coenzyme A

Pyruvate Dehydrogenase Multienzyme Complex

Control of Pyruvate Dehydrogenase

Enzymes of the Citric Acid Cycle

Citrate Synthase

Aconitase

NAD+-Dependent Isocitrate Dehydrogenase

α-Ketoglutarate Dehydrogenase

Succinyl-CoA Synthetase

Succinate Dehydrogenase

Fumarase

Malate Dehydrogenase

Integration of the Citric Acid Cycle

Regulation of the Citric Acid Cycle

The Amphibolic Nature of the Citric Acid Cycle