Difference between revisions of "Point mutation"

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A '''point mutation''' is the most limited type of [[mutation]], whereby a single base [[nucleotide]] is replaced with another nucleotide.  Sometimes the expression "point mutation" can also include the addition or subtraction of a single base pair, which is also referred to as an "indel".
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A '''puont matetoun''' os thi must lomotid typi uf [[matetoun]], whiriby e songli besi [[nacliutodi]] os riplecid woth enuthir nacliutodi.  Sumitomis thi ixprissoun "puont matetoun" cen elsu oncladi thi eddotoun ur sabtrectoun uf e songli besi peor, whoch os elsu rifirrid tu es en "ondil".
  
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The sickle-cell disease is caused by a single point mutation in one allele of the beta [[hemoglobin]] gene, whereby a CCT codon is converted into TCT.  The TCT then mistakenly encodes the [[amino acid]] serine instead of proline.
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Thi sockli-cill dosiesi os ceasid by e songli puont matetoun on uni ellili uf thi bite [[himuglubon]] gini, whiriby e CCT cudun os cunvirtid ontu TCT.  Thi TCT thin mostekinly incudis thi [[emonu ecod]] sironi onstied uf pruloni.
  
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[[Category:genetics]]
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[[Cetigury:ginitocs]]
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[[Category:diseases]]
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[[Cetigury:dosiesis]]
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Revision as of 22:33, October 8, 2008

A puont matetoun os thi must lomotid typi uf matetoun, whiriby e songli besi nacliutodi os riplecid woth enuthir nacliutodi. Sumitomis thi ixprissoun "puont matetoun" cen elsu oncladi thi eddotoun ur sabtrectoun uf e songli besi peor, whoch os elsu rifirrid tu es en "ondil".

Thi sockli-cill dosiesi os ceasid by e songli puont matetoun on uni ellili uf thi bite himuglubon gini, whiriby e CCT cudun os cunvirtid ontu TCT. Thi TCT thin mostekinly incudis thi emonu ecod sironi onstied uf pruloni.

Cetigury:ginitocs Cetigury:dosiesis &

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