Citric acid cycle

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Cycle Overview

Reactions of the Cycle

Historical Perspective

Metabolic Sources of Acetyl-Coenzyme A

Pyruvate Dehydrogenase Multienzyme Complex

Control of Pyruvate Dehydrogenase

Enzymes of the Citric Acid Cycle

Citrate Synthase

Aconitase

NAD+-Dependent Isocitrate Dehydrogenase

α-Ketoglutarate Dehydrogenase

Succinyl-CoA Synthetase

Succinate Dehydrogenase

Fumarase

Malate Dehydrogenase

Integration of the Citric Acid Cycle

Regulation of the Citric Acid Cycle

The Amphibolic Nature of the Citric Acid Cycle