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Hydroxychloroquine (view source)

Revision as of 04:32, April 12, 2020

527 bytes added ,  04:32, April 12, 2020
reduction in binding effect
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According to the website ResearchGate.net: "Several studies have reported that zinc has a broad-spectrum antiviral activity against a variety of viruses. Increased intracellular Zinc concentrations inhibit RNA-dependent RNA polymerases and other proteins essential for the completion of different phases of the virus life cycle. Further, zinc also helps to maintain robust immune responses by producing cytokine and by modulation of immune cell activity."<ref>[https://www.researchgate.net/post/Is_a_combo_of_chloroquine_and_Zinc_a_cure_for_coronavirus Is a combo of chloroquine and Zinc a cure for coronavirus?]</ref>
 
According to the website ResearchGate.net: "Several studies have reported that zinc has a broad-spectrum antiviral activity against a variety of viruses. Increased intracellular Zinc concentrations inhibit RNA-dependent RNA polymerases and other proteins essential for the completion of different phases of the virus life cycle. Further, zinc also helps to maintain robust immune responses by producing cytokine and by modulation of immune cell activity."<ref>[https://www.researchgate.net/post/Is_a_combo_of_chloroquine_and_Zinc_a_cure_for_coronavirus Is a combo of chloroquine and Zinc a cure for coronavirus?]</ref>
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== Reduction in binding effect ==
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Hydroxychlorquine reportedly "directly reduces the binding of antiphospholipid [[antibody]]–β2-glycoprotein I complexes to phospholipid bilayers":<ref>https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2518879/</ref>
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{{[W]e have provided clear evidence that HCQ can dissociate aPL IgG–β2GPI complexes from phospholipid bilayers. Additional studies will be needed to further define the molecular mechanism(s) for this dissociation and its possible role in modifying the APS disease process.}}
 
==See also==
 
==See also==
 
* [[Azithromycin]]
 
* [[Azithromycin]]
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