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In addition to antimicrobial activity, anti-inflammatory, and anti-tumor activities, characterized in several in vitro cell studies and in vivo animal studies. Hinokitiol determined to exert cytotoxicity on several prominent cancer cell lines by inducing autophagic processes.[http://www.kjcls.org/journal/view.html?doi=10.15324/kjcls.2019.51.2.221 [17<nowiki>]</nowiki>][https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5979393/ [18<nowiki>]</nowiki>]
In addition to antimicrobial activity, anti-inflammatory, and anti-tumor activities, characterized in several in vitro cell studies and in vivo animal studies. Hinokitiol determined to exert cytotoxicity on several prominent cancer cell lines by inducing autophagic processes.[http://www.kjcls.org/journal/view.html?doi=10.15324/kjcls.2019.51.2.221 [17<nowiki>]</nowiki>][https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5979393/ [18<nowiki>]</nowiki>]
'''Anti-Cancer'''
This study indicates the inhibitory effect of hinokitiol on the migration of human adenocarcinoma A549 cells. The anticancer properties of hinokitiol are supported by the evaluation of results in the present study, including an increase of Bax/p53 and cytochrome c, and further activation of caspases-9/-3 and antioxidant enzymes CAT and SOD. Moreover, we discovered the inhibitory impact of hinokitiol on the A549 cell migration was accompanied through the downregulation of MMPs-9 and MMP-2. These outcomes can also illustrate a new therapeutic value of hinokitiol in anticancer therapy.