The two Republicans who ran to challenge Sen. Coons were James DeMartino, who the Republican establishment tended to favor,<ref>[https://www.delawareonline.com/story/news/politics/elections/2020/07/28/delaware-republican-endorsements-election-2020-murray-demartino-murphy-hall-pillsbury/5473552002/ Delaware Republican Party makes endorsements amid contention between members, candidates]</ref> and [[Lauren Witzke]],<ref>[https://www.wmdt.com/2020/01/republican-lauren-witzke-challenging-sen-chris-coons/ https://www.wmdt.com/2020/01/republican-lauren-witzke-challenging-sen-chris-coons/]</ref> the more [[populist]] candidate.
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The two Republicans who ran to challenge Sen. Coons were James DeMartino, who the Republican establishment tended to favor,<ref>[https://www.delawareonline.com/story/news/politics/elections/2020/07/28/delaware-republican-endorsements-election-2020-murray-demartino-murphy-hall-pillsbury/5473552002/ Delaware Republican Party makes endorsements amid contention between members, candidates]</ref> and [[Lauren Witzke]],<ref>[https://www.wmdt.com/2020/01/republican-lauren-witzke-challenging-sen-chris-coons/ https://www.wmdt.com/2020/01/republican-lauren-witzke-challenging-sen-chris-coons/]</ref> a more [[populist]] candidate.
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While DeMartino initially held a lead as votes were being counted on the primary election night, Witzke ultimately won with 57% of the vote.<ref name="Delaware U.S. Senate Primary Election Results"/>
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While DeMartino initially held a lead as votes were being counted on the primary election night, Witzke ultimately won with 57% of the vote to face Coons in the general election.<ref name="Delaware U.S. Senate Primary Election Results"/>