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Alkaline hydrolysis (view source)

Revision as of 15:21, June 5, 2007

318 bytes added ,  15:21, June 5, 2007
New page: Alkaline hydrolysis is the cleavage of covalent chemical bonds by a high pH. At high pH, RNA molecules have 2' hydroxyls that attack the 3' phosphodiester bond and degrade th...
Alkaline hydrolysis is the cleavage of [[covalent]] chemical bonds by a high [[pH]].

At high pH, [[RNA]] molecules have 2' hydroxyls that attack the 3' phosphodiester bond and degrade the RNA polymer to monoribonucleotides.

[[DNA]] lacks 2' hydroxyl groups and cannot be hydrolyzed at high pH.
[[Category:Biology]]
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