Changes

'''Ivermectin''' is an off-[[patent]] (generic), inexpensive medication which was originally produced by Merck & Co., Inc. It has also been known by various trade names, including Stromectol and Sklice. It was made commercially available in 1981, and has been widely used since then for a variety of parasitic infections, as well as a few anti-viral applications. Due to its significant safety and effectiveness, it was added to the World Health Organization's List of Essential Medicines.<ref>Kennedy, R. F. (2022). Chapter 8. In The real Anthony Fauci: Bill Gates, Big Pharma, and the Global War on Democracy and Public Health. essay, Skyhorse Publishing.</ref>  

'''Ivermectin''' is an off-[[patent]] (generic), inexpensive medication which was originally produced by Merck & Co., Inc. It has also been known by various trade names, including Stromectol and Sklice. It was made commercially available in 1981, and has been widely used since then for a variety of parasitic infections, as well as a few anti-viral applications. The patent for this self-proclaimed "wonder drug" expired in 1996, and it is now available from over a dozen generic manufacturers, for around $0.40 per dose (as of 2022). Due to its significant safety and effectiveness, it was added to the World Health Organization's List of Essential Medicines. Prior to the COVID-19 pandemic, about 30% of prescriptions in the United States for Ivermectin were for "off-label" use.<ref name="The real Anthony Fauci">Kennedy, R. F. (2022). Chapter 8. The real Anthony Fauci: Bill Gates, Big Pharma, and the Global War on Democracy and Public Health. essay, Skyhorse Publishing.</ref>  

It is also widely considered to be an effective treatment for [[COVID-19]] as suggested by numerous, constantly updated studies compiled online and by peer-reviewed studies worldwide.<ref>https://ivmmeta.com/</ref>  The Chairman of the [[Japan]]ese medical association announced in late August 2021 that physicians should use Ivermectin to treat COVID-19, but it continues to be suppressed by [[liberal]]s in the [[United States]].  "A 5-day course of Ivermectin was found to be safe and effective in treating adult patients with mild COVID-19," according to a study published in a journal posted by the [[NIH]]'s National Library of Medicine.<ref>https://pubmed.ncbi.nlm.nih.gov/33278625/</ref>  Its beneficial biological mechanism has been published by an NIH peer-reviewed article.<ref>https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7996102/</ref>

It is also widely considered to be an effective treatment for [[COVID-19]] as suggested by numerous, constantly updated studies compiled online and by peer-reviewed studies worldwide.<ref>https://ivmmeta.com/</ref>  The Chairman of the [[Japan]]ese medical association announced in late August 2021 that physicians should use Ivermectin to treat COVID-19, but it continues to be suppressed by [[liberal]]s in the [[United States]].  "A 5-day course of Ivermectin was found to be safe and effective in treating adult patients with mild COVID-19," according to a study published in a journal posted by the [[NIH]]'s National Library of Medicine.<ref>https://pubmed.ncbi.nlm.nih.gov/33278625/</ref>  Its beneficial biological mechanism has been published by an NIH peer-reviewed article.<ref>https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7996102/</ref>

The [[NIH]] wrote:

The [[NIH]] wrote:

{{cquote|Ivermectin is a drug that many people will never have heard of. Yet thousands of villagers of all ages in communities scattered throughout the remotest parts of [[Africa]] and [[Latin America]] know its name, and some experts regard it as one of the greatest health interventions of the past 50 years. Ivermectin was brought to the commercial market place for multi-purpose use in animal health in 1981. Six years later it was registered for human use. This remarkable compound has improved the lives and productivity of billions of humans, livestock and pets around the globe, and promises to help consign to the history books two devastating and disfiguring diseases that have plagued people throughout the tropics for generations–while new uses for it are continually being found.<ref>https://mustreadalaska.com/from-local-news-to-usa-today-mainstream-media-drags-kenai-mayor-for-ivermectin-remark-but-nih-scientific-papers-say-its-a-wonder-drug-with-expanding-uses/</ref>}}

{{cquote|Ivermectin is a drug that many people will never have heard of. Yet thousands of villagers of all ages in communities scattered throughout the remotest parts of [[Africa]] and [[Latin America]] know its name, and some experts regard it as one of the greatest health interventions of the past 50 years. Ivermectin was brought to the commercial market place for multi-purpose use in animal health in 1981. Six years later it was registered for human use. This remarkable compound has improved the lives and productivity of billions of humans, livestock and pets around the globe, and promises to help consign to the history books two devastating and disfiguring diseases that have plagued people throughout the tropics for generations–while new uses for it are continually being found.<ref>https://mustreadalaska.com/from-local-news-to-usa-today-mainstream-media-drags-kenai-mayor-for-ivermectin-remark-but-nih-scientific-papers-say-its-a-wonder-drug-with-expanding-uses/</ref>}}

== Studies ==

== Studies ==

Researchers at Queen Mary, University of London, published a paper in August 2021 which concluded that:

Researchers at Queen Mary, University of London, published a paper in August 2021 which concluded that:

{{cquote|from the Bayesian meta-analysis for patients with severe Covid-19, the mean probability of death without ivermectin treatment is 22.9%, whilst with the application of ivermectin treatment it is 11.7%<ref>https://www.researchgate.net/publication/353973030_Bayesian_hypothesis_testing_and_hierarchical_modelling_of_ivermectin_effectiveness_in_treating_Covid-19</ref>}}

{{cquote|from the Bayesian meta-analysis for patients with severe Covid-19, the mean probability of death without ivermectin treatment is 22.9%, whilst with the application of ivermectin treatment it is 11.7%<ref>https://www.researchgate.net/publication/353973030_Bayesian_hypothesis_testing_and_hierarchical_modelling_of_ivermectin_effectiveness_in_treating_Covid-19</ref>}}

==Randomized Trial Negative Results==

==Randomized Trial Negative Results==

Double-blind, randomized trial that included 476 patients and conducted at a single site in Cali, Colombia, did not support the use of ivermectin for treatment of mild COVID-19. Test patients were given drastically larger doses than would usually be prescribed, which resulted in side effects from over-dosing.<ref>Kennedy, R. F. (2022). Chapter 8. In The real Anthony Fauci: Bill Gates, Big Pharma, and the Global War on Democracy and Public Health. essay, Skyhorse Publishing.</ref> Larger trials may be needed to understand the effects of ivermectin on other clinically relevant outcomes.<ref>https://jamanetwork.com/journals/jama/fullarticle/2777389</ref>

Double-blind, randomized trial that included 476 patients and conducted at a single site in Cali, Colombia, did not support the use of ivermectin for treatment of mild COVID-19. Test patients were given drastically larger doses than would usually be prescribed, which resulted in side effects from over-dosing.<ref name="The real Anthony Fauci">Kennedy, R. F. (2022). Chapter 8. The real Anthony Fauci: Bill Gates, Big Pharma, and the Global War on Democracy and Public Health. essay, Skyhorse Publishing.</ref> Larger trials may be needed to understand the effects of ivermectin on other clinically relevant outcomes.<ref>https://jamanetwork.com/journals/jama/fullarticle/2777389</ref>

==University of Oxford Study==

==University of Oxford Study==

The University of Oxford in the UK has added ivermectin to the Platform Randomised Trial of Treatments in the Community for Epidemic and Pandemic Illnesses (PRINCIPLE) study for the treatment of COVID-19. In small pilot studies, early use of ivermectin was able to lower viral load and the duration of symptoms in some mild COVID-19 patients.<ref>https://www.clinicaltrialsarena.com/news/ivermectin-principle-trial-covid/</ref>

The University of Oxford in the UK has added ivermectin to the Platform Randomised Trial of Treatments in the Community for Epidemic and Pandemic Illnesses (PRINCIPLE) study for the treatment of COVID-19. In small pilot studies, early use of ivermectin was able to lower viral load and the duration of symptoms in some mild COVID-19 patients.<ref>https://www.clinicaltrialsarena.com/news/ivermectin-principle-trial-covid/</ref>

== See also ==

== See also ==