| − | In superbly massive doses, caffeine is lethal. A fatal dose of caffeine has been calculated to be more than 10 grams (about 170 mg/kg body weight) - this would be equivalent to drinking 80 to 100 cups of coffee in rapid succession - a feat only [[Voltaire]] is alleged to have acheieved. | + | In superbly massive doses, caffeine is lethal. A fatal dose of caffeine has been calculated to be more than 10 grams (about 170 mg/kg body weight) - this would be equivalent to drinking 80 to 100 cups of coffee in rapid succession - a feat only [[Voltaire]] is alleged to have achieved. |
| | Caffeine enters the bloodstream through the [[stomach]] and [[small intestine]] and can have its effects as soon as 15 minutes after it is consumed. Once in the body, caffeine will stay around for hours: it takes about 6 hours for one half of the caffeine to be eliminated. | | Caffeine enters the bloodstream through the [[stomach]] and [[small intestine]] and can have its effects as soon as 15 minutes after it is consumed. Once in the body, caffeine will stay around for hours: it takes about 6 hours for one half of the caffeine to be eliminated. |
| − | Caffeine can be found in many drinks, foods, and drugs. Americans consume about 45,000,000 pounds of caffeine each year. In the [[United States]], coffee drinkers drink an average of 2.6 cups per day. Total caffeine intake for coffee drinkers was 363.5 mg per day - this includes caffeine from coffee and other sources like soft drinks, food and drugs. Non-coffee drinkers also consume plenty of caffeine: former coffee drinkers get about 107 mg per day and people who have never had coffee get about 91 mg per day. <ref>Schreiber et al., Measurement of coffee and caffeine intake: Implications for epidemiolgic research, Preventive Medicine, 17:280-294, 1988 and Chou, T., Wake up and smell the coffee. Caffeine, coffee and the medical consequences, West. J. Med., 157:544-553, 1992</ref> | + | Caffeine can be found in many drinks, foods, and drugs. Americans consume about 45,000,000 pounds of caffeine each year. In the [[United States]], coffee drinkers drink an average of 2.6 cups per day. Total caffeine intake for coffee drinkers was 363.5 mg per day - this includes caffeine from coffee and other sources like soft drinks, food and drugs. Non-coffee drinkers also consume plenty of caffeine: former coffee drinkers get about 107 mg per day and people who have never had coffee get about 91 mg per day. <ref>Schreiber et al., Measurement of coffee and caffeine intake: Implications for epidemiological research, Preventive Medicine, 17:280-294, 1988 and Chou, T., Wake up and smell the coffee. Caffeine, coffee and the medical consequences, West. J. Med., 157:544-553, 1992</ref> |