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Talk:Flaws in Richard Lenski Study (view source)
Revision as of 04:42, July 14, 2008
, 04:42, July 14, 2008→Marginally significant: reply to Murray
: Your defense of Lenski per point #1 is contradicted by the paper's own abstract, and by the comments by the other Lenski defender below. In point #3, proper weighting is needed to combine multiple studies. In point #5, you don't cite any authority for the unscientific claim of being "marginally significant."--[[User:Aschlafly|Aschlafly]] 20:45, 13 July 2008 (EDT)
: Your defense of Lenski per point #1 is contradicted by the paper's own abstract, and by the comments by the other Lenski defender below. In point #3, proper weighting is needed to combine multiple studies. In point #5, you don't cite any authority for the unscientific claim of being "marginally significant."--[[User:Aschlafly|Aschlafly]] 20:45, 13 July 2008 (EDT)
::Define "proper weighting". Are you referring to how they interpreted the sum of the work or to a specific analysis? You're right, I didn't cite any scientific authority. Here's one: Motulsky, H. (1995). ''Intuitive Biostatistics'', Oxford Univ. Press. Chapter 12. Also, try searching for the phrase in Google Scholar or PubMed, you'll find plenty of uses of it. It's a shorthand way of describing an effect that came close to the arbitrary threshold for statistical significance but did not reach it. [[User:Murray|Murray]] 21:55, 13 July 2008 (EDT)
::Define "proper weighting". Are you referring to how they interpreted the sum of the work or to a specific analysis? You're right, I didn't cite any scientific authority. Here's one: Motulsky, H. (1995). ''Intuitive Biostatistics'', Oxford Univ. Press. Chapter 12. Also, try searching for the phrase in Google Scholar or PubMed, you'll find plenty of uses of it. It's a shorthand way of describing an effect that came close to the arbitrary threshold for statistical significance but did not reach it. [[User:Murray|Murray]] 21:55, 13 July 2008 (EDT)
::: You seem unwilling to accept that Point #1 identifies a clear mistake between the figure and the abstract in the paper, which requires correction by Lenski or PNAS. Given that unwillingness, I doubt it will productive discussing the other mistakes further with you. You're right that other usage of the dubious concept of "marginally significant" can be found on the internet, but the first link to such usage on my internet search for it returned the non-rigorous "Intuitive Biostatistics" and the second link returned a criticism of the concept similar to the criticism express here. [http://annhyg.oxfordjournals.org/cgi/reprint/49/1/93-a.pdf] --[[User:Aschlafly|Aschlafly]] 00:42, 14 July 2008 (EDT)
== Richard Lenski incorrectly included generations of the E. coli already known to contain Cit+ variants in his experiments.[3] Once these generations are removed from the analysis, the data disprove Len ==
== Richard Lenski incorrectly included generations of the E. coli already known to contain Cit+ variants in his experiments.[3] Once these generations are removed from the analysis, the data disprove Len ==