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Talk:Flaws in Richard Lenski Study (view source)
Revision as of 22:55, July 14, 2008
, 22:55, July 14, 2008→Richard Lenski incorrectly included generations of the E. coli already known to contain Cit+ variants in his experiments.[3] Once these generations are removed from the analysis, the data disprove Len
::I count at least four distinct diagnostic methods used in the paper for distinguishing whether clones are Cit+. One in particular they describe as being very sensitive to weakly citrate-using cells. It's not that I 'think' Blount et al. claim they started with Cit- cells. They say that in the 'Supporting information' document.
::I count at least four distinct diagnostic methods used in the paper for distinguishing whether clones are Cit+. One in particular they describe as being very sensitive to weakly citrate-using cells. It's not that I 'think' Blount et al. claim they started with Cit- cells. They say that in the 'Supporting information' document.
::Andy, for tonight, I'll leave it as an exercise for you to answer your own question of how one might test a colony to be sure that is was Cit-. Use the paper if you'd like or present another means. Tomorrow evening I'll cite the methods Blount used in the paper.
::Andy, for tonight, I'll leave it as an exercise for you to answer your own question of how one might test a clone to be sure that is was Cit-. Use the paper if you'd like or present another means. Tomorrow evening I'll cite the methods Blount used in the paper.
::Meanwhile, here's another question to ponder: If the colonies used to start the 'replay' cultures were Cit+ at the start, why is it that no Cit+ cells were found in such cultures before 750 generations? These cultures were all started from single clones which must have either had the Cit+ phenotype or not.--[[User:Argon|Argon]] 18:38, 14 July 2008 (EDT)
::Meanwhile, here's another question to ponder: If the colonies used to start the 'replay' cultures were Cit+ at the start, why is it that no Cit+ cells were found in such cultures before 750 generations? These cultures were all started from single clones which must have either had the Cit+ phenotype or not.--[[User:Argon|Argon]] 18:38, 14 July 2008 (EDT)