nsJudgesRO, nsJudgesRW, nsJudges_talkRO, nsJudges_talkRW
461
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Line 6:
Line 6: − The suspected cause must be strongly associated with the disease.+ − The molecular version of this postulate states that an epidemiological association exists between presence of a trait and virulence, that a specific mutation be constructed to inhibit the function resulting in decrease − in virulence, and finally that the mutation be complemented in trans with only the wild-type allele of the − mutated gene provided on a recombinant plasmid.
→Epidemiological association: Simplified
===Epidemiological association===
===Epidemiological association===
An association should exist between a microorganism and disease (i.e., the organism is identified or recovered from patients).
===Isolation===
===Isolation===