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Systematic theological instruction was inaugurated in 1721 and by 1827 Harvard became a nucleus of theological teaching in New England.<ref>http://www.reference.com/browse/Harvard</ref>

Systematic theological instruction was inaugurated in 1721 and by 1827 Harvard became a nucleus of theological teaching in New England.<ref>http://www.reference.com/browse/Harvard</ref>

The departure of Increase Mather from the presidency in 1701 marked the beginning of a long term struggle between orthodoxy and liberalism. The takeover of Harvard by the Unitarians in 1805 resulted in the secularization of the American university. Before the mid 1800's, Harvard would become what was basically described as the "Unitarian Vatican." <ref>[http://www.forerunner.com/forerunner/X0100_Christianity_in_U.S..html A Brief History of Christian Influence in U.S. Colleges]</ref>  

The departure of Increase Mather from the presidency in 1701 marked the beginning of a long term struggle between orthodoxy and liberalism.  Harvard's first secular president was John Leverett, who began his term in 1708.  Leverett left the curriculum largely intact and sought to keep the College independent of the overwhelming influence of any single sect <ref>[http://www.president.harvard.edu/history/07_leverett.php John Leverett - History - Office of the President]</ref>. The takeover of Harvard by the Unitarians in 1805 resulted in the secularization of the American university. Before the mid 1800's, Harvard would become what was basically described as the "Unitarian Vatican." <ref>[http://www.forerunner.com/forerunner/X0100_Christianity_in_U.S..html A Brief History of Christian Influence in U.S. Colleges]</ref>  

Radical changes in educational scope and growth were in seen during the 40 year reign of Harvard president Charles W. Eliot (1869-1909).

Radical changes in educational scope and growth were in seen during the 40 year reign of Harvard president Charles W. Eliot (1869-1909).