| − | As stated on WebMD<ref>http://www.webmd.com/brain/charcot-marie-tooth-disease</ref>, '''Charcot-Marie-Tooth Disease''' (abbreviated '''CMT''') is "''a '''group of disorders''' in which the '''motor and/or [[sensory peripheral nerves]]''' are '''affected''', resulting in '''muscle weakness''' and '''[[atrophy]]''', as well as '''[[sensory loss]]'''. These manifestions occur first in the distal legs and later in the hands. The [[nerve cells]] in individuals with this disorder are not able to send electrical signals properly because of abnormalities in the nerve axon or abnormalities in the insulation ([[myelin]]) around the axon. Specific gene mutations are responsible for the abnormal function of the peripheral nerves. Charcot Marie Tooth disease can be inherited in an [[autosomal dominant]], [[autosomal recessive]] or [[X-linked mode of inheritance]].''" It is also known as [[Hereditary Motor and Sensory Neuropathy]] ([[HMSN]]) or [[Peroneal Muscular Atrophy]] ([[PMA]])<ref>http://www.mdausa.org/disease/cmt.html</ref>, but the disease in general is accepted by the community who has it as not receiving a great deal of publicity<ref>http://www.youtube.com/watch?v=8xAgPRYO3XY</ref>, they say things like "what bothers me is when I tell a doctor about CMT.....and get that blank, dull look.....they have no clue."<ref>http://www.youtube.com/watch?v=8xAgPRYO3XY</ref> -tickyul, [[YouTube]] user. [[John 3:17]] | + | As stated on WebMD<ref>http://www.webmd.com/brain/charcot-marie-tooth-disease</ref>, '''Charcot-Marie-Tooth Disease''' (abbreviated '''CMT''') is "''a '''group of disorders''' in which the '''motor and/or sensory peripheral nerves''' are '''affected''', resulting in '''muscle weakness''' and '''[[atrophy]]''', as well as '''[[sensory loss]]'''. These manifestions occur first in the distal legs and later in the hands. The [[nerve cells]] in individuals with this disorder are not able to send electrical signals properly because of abnormalities in the nerve axon or abnormalities in the insulation ([[myelin]]) around the axon. Specific gene mutations are responsible for the abnormal function of the peripheral nerves. Charcot Marie Tooth disease can be inherited in an [[autosomal dominant]], [[autosomal recessive]] or [[X-linked mode of inheritance]].''" |