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*"CDC has no limits on the use of hydroxychloroquine for the prevention of malaria. When hydroxychloroquine is used at higher doses for many years, a rare eye condition called retinopathy has occurred. People who take hydroxychloroquine for more than five years should get regular eye exams."
 
*"CDC has no limits on the use of hydroxychloroquine for the prevention of malaria. When hydroxychloroquine is used at higher doses for many years, a rare eye condition called retinopathy has occurred. People who take hydroxychloroquine for more than five years should get regular eye exams."
 
== Zinc and coronavirus ==
 
== Zinc and coronavirus ==
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The usefulness of zinc to HCQ treatments is explained by a study published in September 2020, "Hydroxychloroquine, a drug used initially in the management of COVID-19, is an ionophore that transports Zinc across the hydrophobic cell  membrane. Moreover,  evidences  specifically  suggest  that  Zinc  supplemented  with antiviral drugs  containing  Zinc-ionophores  precisely  targets  and  binds  to  SARS-CoV-2 preventing its replication within the infected host cells2."<ref>https://www.sciencedirect.com/science/article/pii/S120197122030730X</ref>
    
According to the website ResearchGate.net: "Several studies have reported that zinc has a broad-spectrum antiviral activity against a variety of viruses. Increased intracellular Zinc concentrations inhibit RNA-dependent RNA polymerases and other proteins essential for the completion of different phases of the virus life cycle. Further, zinc also helps to maintain robust immune responses by producing cytokine and by modulation of immune cell activity."<ref>[https://www.researchgate.net/post/Is_a_combo_of_chloroquine_and_Zinc_a_cure_for_coronavirus Is a combo of chloroquine and Zinc a cure for coronavirus?]</ref>
 
According to the website ResearchGate.net: "Several studies have reported that zinc has a broad-spectrum antiviral activity against a variety of viruses. Increased intracellular Zinc concentrations inhibit RNA-dependent RNA polymerases and other proteins essential for the completion of different phases of the virus life cycle. Further, zinc also helps to maintain robust immune responses by producing cytokine and by modulation of immune cell activity."<ref>[https://www.researchgate.net/post/Is_a_combo_of_chloroquine_and_Zinc_a_cure_for_coronavirus Is a combo of chloroquine and Zinc a cure for coronavirus?]</ref>
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