Difference between revisions of "Caffeine"

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'''Caffeine''' is the most popular [[drug]]<ref>
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'''Caffeine''' is natural plant [[alkaloid]] found in the coffee bean, the tea leaf, the [[kola]] nut, and the [[cacao]] podin. [[Coffee]], [[tea]], [[cocoa]], [[chocolate]], [[soft drink]]s, and some drugs all contain caffeine, and when consumed, it behaves as a central nervous system [[stimulant]]. Pure caffeine is odorless and has a bitter taste. Caffeine, in the form of tea or coffee, is the worlds most widely used and popular drug.<ref>https://www.theatlantic.com/science/archive/2016/03/worlds-most-popular-drug/474831/</ref>
Chemical formula: 3,7-dihydro-1,3,8-trimethyl-1H-purine-2,6,-dione OR 1,3,7-trimethylxanthine </ref>
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in the world. People consume caffeine in [[coffee]], [[tea]], [[cocoa]], [[chocolate]], [[soft drink]]s, and some drugs. The source of caffeine is either the coffee bean, the tea leaf, the elusive kola nut, or the cacao pod. Pure caffeine is odorless and has a bitter taste.
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==Caffeine effects==
 
==Caffeine effects==
Caffeine is a central nervous system [[stimulant]]. In moderate doses, caffeine may:
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[[File:Caffeine metabolites.svg.png|thumbnail|In the liver, caffeine is metabolized into three main compounds]]
* Increase alertness
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In moderate doses, caffeine:
* Reduce fine motor coordination
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* Increases alertness
* Cause [[insomnia]]
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* Reduces fine motor coordination
* Cause anxiety and dizziness
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* May cause [[insomnia]]
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* May cause anxiety and dizziness
 
* Potentiates the action of epinephrine causing increased heart rate and blood pressure
 
* Potentiates the action of epinephrine causing increased heart rate and blood pressure
 
* Stimulates Dopamine secretion
 
* Stimulates Dopamine secretion
 
* Enhances gastric acid secretion  
 
* Enhances gastric acid secretion  
* Promotes diuresis
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* Promotes diuresis and may contribute to dehydration
  
In superbly massive doses, caffeine is lethal. A fatal dose of caffeine has been calculated to be more than 10 grams (about 170 mg/kg body weight) - this would be equivalent to  drinking 80 to 100 cups of coffee in rapid succession - a feat only [[Voltaire]] is alleged to have achieved.
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Caffeine enters the bloodstream through absorption in the [[stomach]] and [[small intestine]] and, like other psychoactive compounds (e.g. nicotine and ethanol), easily crosses the [[blood brain barrier]]. Caffeine's main biochemical affect is competitive inhibition of adenosine receptors ([[antagonist]] action). [[Adenosine]], which shares a similar chemical structure with caffeine, in the central nervous system is important for promoting sleep. Effects may be seen within 15 minutes of consumption. Once in the body, caffeine will stay around for hours: it takes about six hours for one half of the caffeine to be eliminated.
  
Caffeine enters the bloodstream through the [[stomach]] and [[small intestine]] and can have its effects as soon as 15 minutes after it is consumed. Once in the body, caffeine will stay around for hours: it takes about 6 hours for one half of the caffeine to be eliminated.
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Studies show that caffeine causes physical dependence (addiction); whether beneficial or not, dependence, addiction and withdrawal are all properties of drugs, and it is only a matter of degree. One way to tell if someone "needs" that cup of coffee or bottle of [[Mountain Dew]] is to take it away from them and then see if they have any withdrawal symptoms. Typical withdrawal symptoms associated with caffeine are the headaches, fatigue, and muscle pains. These symptoms can occur within 24 hours after the last dose of caffeine. One study has stated that the minimum consumption of caffeine for physical dependence is 4 cups of coffee per day. Other studies say that a few more cups of coffee are needed to develop dependence.
  
Some studies show that caffeine causes physical dependence (addiction). One way to tell if someone "needs" that cup of coffee or bottle of [[Mountain Dew]] is to take it away from them and then see if they have any withdrawal symptoms. Typical withdrawal symptoms associated with caffeine are the headaches, fatigue, and muscle pains. These symptoms can occur within 24 hours after the last dose of caffeine. One study has stated that the minimum consumption of caffeine for physical dependence is 4 cups of coffee per day. Other studies say that a few more cups of coffee are needed to develop dependence.
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Excessive caffeine consumption over time can lead to kidney stones.
 
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==Origin Legend==
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Coffee was discovered around 850 A.D. in upper [[Egypt]] by a goat herder named Khaldi. One night, Khaldi's goats did not return home. When he found his goats, Khaldi saw them dancing around a shrub with red berries (coffee beans). After Khaldi tried some of the berries, he started to dance too. Khaldi spoke with some monks who used the berries to make a drink and coffee was born.
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==Modern Consumption==
 
==Modern Consumption==
 
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[[Image:MG caffeine in drinks.jpg|right|300px]]
Caffeine can be found in many drinks, foods, and drugs. Americans consume about 45,000,000 pounds of caffeine each year. In the [[United States]], coffee drinkers drink an average of 2.6 cups per day. Total caffeine intake for coffee drinkers was 363.5 mg per day - this includes caffeine from coffee and other sources like soft drinks, food and drugs. Non-coffee drinkers also consume plenty of caffeine: former coffee drinkers get about 107 mg per day and people who have never had coffee get about 91 mg per day. <ref>Schreiber et al., Measurement of coffee and caffeine intake: Implications for epidemiological research, Preventive Medicine, 17:280-294, 1988 and Chou, T., Wake up and smell the coffee. Caffeine, coffee and the medical consequences, West. J. Med., 157:544-553, 1992</ref>
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Caffeine can be found in many drinks, foods, and drugs. Americans consume about 45,000,000 pounds of caffeine each year. In the [[United States]], coffee drinkers drink an average of 2.6 cups per day. Total caffeine intake for coffee drinkers was 363.5&nbsp;mg per day - this includes caffeine from coffee and other sources like soft drinks, food and drugs. Non-coffee drinkers also consume plenty of caffeine: former coffee drinkers get about 107&nbsp;mg per day and people who have never had coffee get about 91&nbsp;mg per day.<ref>Schreiber et al., Measurement of coffee and caffeine intake: Implications for epidemiological research, Preventive Medicine, 17:280-294, 1988 and Chou, T., Wake up and smell the coffee. Caffeine, coffee and the medical consequences, West. J. Med., 157:544-553, 1992</ref>
  
 
==References==
 
==References==

Revision as of 03:35, February 21, 2023

Caffeine is natural plant alkaloid found in the coffee bean, the tea leaf, the kola nut, and the cacao podin. Coffee, tea, cocoa, chocolate, soft drinks, and some drugs all contain caffeine, and when consumed, it behaves as a central nervous system stimulant. Pure caffeine is odorless and has a bitter taste. Caffeine, in the form of tea or coffee, is the worlds most widely used and popular drug.[1]

Caffeine effects

In the liver, caffeine is metabolized into three main compounds

In moderate doses, caffeine:

  • Increases alertness
  • Reduces fine motor coordination
  • May cause insomnia
  • May cause anxiety and dizziness
  • Potentiates the action of epinephrine causing increased heart rate and blood pressure
  • Stimulates Dopamine secretion
  • Enhances gastric acid secretion
  • Promotes diuresis and may contribute to dehydration

Caffeine enters the bloodstream through absorption in the stomach and small intestine and, like other psychoactive compounds (e.g. nicotine and ethanol), easily crosses the blood brain barrier. Caffeine's main biochemical affect is competitive inhibition of adenosine receptors (antagonist action). Adenosine, which shares a similar chemical structure with caffeine, in the central nervous system is important for promoting sleep. Effects may be seen within 15 minutes of consumption. Once in the body, caffeine will stay around for hours: it takes about six hours for one half of the caffeine to be eliminated.

Studies show that caffeine causes physical dependence (addiction); whether beneficial or not, dependence, addiction and withdrawal are all properties of drugs, and it is only a matter of degree. One way to tell if someone "needs" that cup of coffee or bottle of Mountain Dew is to take it away from them and then see if they have any withdrawal symptoms. Typical withdrawal symptoms associated with caffeine are the headaches, fatigue, and muscle pains. These symptoms can occur within 24 hours after the last dose of caffeine. One study has stated that the minimum consumption of caffeine for physical dependence is 4 cups of coffee per day. Other studies say that a few more cups of coffee are needed to develop dependence.

Excessive caffeine consumption over time can lead to kidney stones.

Modern Consumption

MG caffeine in drinks.jpg

Caffeine can be found in many drinks, foods, and drugs. Americans consume about 45,000,000 pounds of caffeine each year. In the United States, coffee drinkers drink an average of 2.6 cups per day. Total caffeine intake for coffee drinkers was 363.5 mg per day - this includes caffeine from coffee and other sources like soft drinks, food and drugs. Non-coffee drinkers also consume plenty of caffeine: former coffee drinkers get about 107 mg per day and people who have never had coffee get about 91 mg per day.[2]

References

  1. https://www.theatlantic.com/science/archive/2016/03/worlds-most-popular-drug/474831/
  2. Schreiber et al., Measurement of coffee and caffeine intake: Implications for epidemiological research, Preventive Medicine, 17:280-294, 1988 and Chou, T., Wake up and smell the coffee. Caffeine, coffee and the medical consequences, West. J. Med., 157:544-553, 1992