Vladimir Zelenko's coronavirus treatment

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Dr. Zelenko has successfully used hydroxychloroquine (chemical diagram shown), antibiotics and zinc to treat coronavirus patients.

Zev Vladimir Zelenko, M.D. is a New York State doctor who has treated over 1,450 coronavirus patients using hydroxychloroquine, azithromycin and zinc sulfate with 99.9% success rate (2 deaths).[1] He explained his treatment in an open letter to President Trump.

With his first 350 coronavirus patients in March of 2020, Zelenko had a 100% success using hydroxychloroquine, azithromycin and zinc.[2] There were no hospitalizations, intubations or deaths among Zelenko's first 350 patients.[3] On March 27, 2020, Zelenko indicated that he treated 699 patients with no deaths or intubations, whereas the national average in the United States is 1.5% of coronavirus patients dying.[4] As of March 27, 2020, four patients of Dr. Zelenko have been hospitalized with pneumonia, and none of them required respirators.[4]

Dr. Vladimir Zelenko's treatment resulted in various patients' shortness-of-breath issues being resolved in as early as four hours and on average 12 hours.[5]

On May 30, 2020, the Grand Rapids Herald-Review stated:

Dr. Vladimir Zelenko serves as a Primary Care Physician in suburban New York City—the epicenter of this outbreak. “I knew that the virus would hit our area hard due to our population density—we have 32,000 people living in one square mile. So I did my own research looking at what had been done in other countries that experienced the virus before us as well as looking at treatments developed for the SARS outbreak in 2003 (another coronavirus). I developed my own protocol of a three drug cocktail: HCL, Azithromycin, and Zinc. In the last few weeks I have seen 1,450 patients with COVID symptoms. I divided my patients into two groups: high risk and low risk. The low risk patients (under age 60 and healthy) statistically get better without treatment, so I sent them home to rest and get over the virus. I gave my drug cocktail to 405 high risk patients (over age 60 or with underlying health problems) whose conditions were most severe. The accepted rate of COVID mortality at that time for high risk patients was 5%, so if I had just relied on ventilators I could have expected to see 20 of my patients die. But using these three drugs I only lost two patients, one of which was very old and had been chronically ill. This was a significant order of magnitude better than expected outcomes.”

Dr. Zelenko explains the rationale behind his treatment program. “The zinc is what kills the virus and zinc occurs naturally in the body but has a hard time penetrating the cell where the virus lives. What the hydroxychloroquine does is open a channel into the cell so the zinc can enter and stop the virus from replicating. Adding an extra dose of zinc to the cocktail has been shown to improve outcomes by about 25%. Meanwhile, the azithromycin stands guard to combat any secondary bacterial infection that may crash the party and cause pneumonia.”

After seeing the effectiveness of his treatment regimen, Dr. Zelenko stated, “I realized what I had, and I felt like a front line soldier who had stumbled across some very important intelligence—some valuable information that needed to be communicated to the 5-star general because that information could be used to win the war.”

Within a few weeks, Dr. Zelenko had published video reports of his findings and was in touch not only with the US Coronavirus Taskforce, but with over a dozen governments around the world from Russia, to South Africa, to Peru. Four weeks ago the government of Brazil began implementing Dr. Zelenko’s protocol, and he explains their results: “One week ago the Brazilians published a study revealing a 95% reduction in deaths after this drug cocktail was introduced for use in their government hospitals.”[6]

Hydroxychloroquine and coronavirus

The Food and Drug Administration (FDA) allows hydroxychloroquine to be used as an off-label coronavirus treatment.

According to WebMD.com: "The practice, called 'off-label' prescribing, is entirely legal and very common. More than one in five outpatient prescriptions written in the U.S. are for off-label therapies."[7]

Hydroxychloroquine allows zinc to penetrate the cellular wall to a larger degree.[8] Zinc is an antiviral.[9]

Zinc and coronavirus

Zinc (Zn) is one of the chemical elements and a mineral essential for bodily health. But it is a metal, and in order for it to be transmitted around the body and available for metabolic use, it must be present in a chemically reacted form called an ion. Zinc, the element, has two electrons in the outer shell of each atom. When each zinc atom combines with a non-metallic molecule lacking two electrons from having a complete outer shell or complete binding site, it loses those electrons, and they are gained by the non-metal, the two forming a chemical salt. The ionic zinc can then move freely and interact with other non-metals and participate in diverse chemical reactions.

In its metabolic use, that non-metal part of the salt can be any kind that is not harmful to the body. However in the science of medical testing, one single kind of non-metal ought to be chosen to insure that improvements or detriments to the body found in testing is not caused by variations in that non-metal, but rather the effectiveness of the metallic ion. Even the same non-metal itself should be one that is thought to be inert, for the same reason, and the non-metal that Dr. Zelenko chose was the elementary compound sulfate (SO4).

According to the website ResearchGate.net: "Several studies have reported that zinc has a broad-spectrum antiviral activity against a variety of viruses. Increased intracellular Zinc concentrations inhibit RNA-dependent RNA polymerases and other proteins essential for the completion of different phases of the virus life cycle. Further, zinc also helps to maintain robust immune responses by producing cytokine and by modulation of immune cell activity."[10]

Azithromycin and coronavirus

Azithromycin is a broad-spectrum antibiotic.[11]

For treating coronavirus (Covid-19) patients, the pharmaceutical company Pfizer announced positive data for the use of its drug azithromycin (Zithromax) when used in combination with anti-malarial drug hydroxychloroquine.[12]

A clinical trial was performed in France with 20 patients, six of which were also administered with azithromycin.[13]

According to Drugs.com:

The World Health Organization (WHO) is very clear that antibiotics do not work against viruses, only bacteria, and yet health care providers are using antibiotics in some patients with COVID-19. This is because:

Patients with viral pneumonia can develop a secondary bacterial infection that may need to be treated with an antibiotic, although this complication is reported to be uncommon early on in the course of COVID-19 pneumonia.

If treatment is required for a secondary bacterial infection then a range of antibiotics can be used such as penicillins (ampicillin plus sulbactam [Unasyn], piperacillin plus tazobactam [Zosyn]), macrolides (azithromycin), cephalosporins (ceftriaxone [Rocephin]), aminoglycosides (tobramycin) and glycopeptides (vancomycin [Vancocin HCL]) for example. Often a combination of two different antibiotics is used.

Azithromycin is also thought to have antiviral and anti-inflammatory activity and may work synergistically with other antiviral treatments. In in vitro laboratory studies azithromycin has demonstrated antiviral activity against Zika virus and against rhinoviruses, which cause the common cold.[14]

Dr. Vladmir Zelenko treats his coronavirus patients in his office as an early intervention

Dr. Zelenko treats his coronavirus patients in his office and gives his treatment protocol for some patients who are experiencing shortness of breath.[15][16] For milder cases of coronavirus, he does not use the combination of hydroxychloroquine, azithromycin and zinc.[17][18]

As noted above, Dr. Vladimir Zelenko's treatment resulted in various patients' shortness-of-breath issues being resolved in as early as four hours and on average 12 hours.[5]

Zelenko believes that the majority of the young and healthy people with no preexisting conditions that make them vulnerable to the coronavirus are able to recover from coronavirus without the use of his treatment of hydroxychloroquine, azithromycin and zinc.[19]

Because Zelenko uses his treatment as an early intervention, he uses "slightly lower doses" of hydroxychloroquine and azithromycin than are commonly used to treat coronavirus patients that are being treated in the hospitals.[20]

Zelenko indicates his treatment of hydroxychloroquine, azithromycin and zinc reduces the viral load of his patients, and that it aids the body's immune system, so it has time to combat the coronavirus infection.[21]

Zelenko uses his treatment as an early intervention to prevent lung damage and endangerment to life caused by acute respiratory distress syndrome (ARDS).[22][23]

Zelenko argues that many hospitals are being inundated with patients, so his in-office treatments are a useful means of alleviating pressure on the hospital system.[24][25] In addition, Zelenko argues that many medical supplies are experiencing shortages.[26]

Philippine Star on Dr. Zelenko's coronavirus treatment

According to The Philippine Star:

REGARDING Vladimir Zelenko, the 46-year-old family doctor who gained attention after he reported a 100-percent COVID-19 recovery score, here is a part of his March 23 open letter “to all medical professionals around the world” (copy sent to President Trump):

“My name is Dr. Zev Zelenko and I practice medicine in Monroe, NY. For the last 16 years, I have cared for approximately 75 percent of the adult population of Kiryas Joel, which is a very close-knit community of approximately 35,000 people in which the infection spreads rapidly and unchecked prior to the imposition of social distancing.

“As of today my team has tested approximately 200 people from this community for COVID-19, and 65 percent of the results have been positive. If extrapolated to the entire community, that means more than 20,000 people are infected at the present time. Of this group, I estimate that there are 1,500 patients who are in the high-risk category (i.e. >60, immunocompromised, comorbidities, etc).

“Given the urgency of the situation, I developed the following treatment protocol in the pre-hospital setting and have seen only positive results:

1. Any patient with shortness of breath regardless of age is treated.

2. Any patient in the high-risk category even with just mild symptoms is treated.

3. Young, healthy and low-risk patients even with symptoms are not treated (unless their circumstances change and they fall into category 1 or 2).

“My out-patient treatment regimen is as follows:

1. Hydroxychloroquine 200mg twice a day for five days.

2. Azithromycin 500mg once a day for five days.

3. Zinc sulfate 220mg once a day for five days. [Editor's note: 50mg of elemental zinc, as it is commonly sold as a vitamin, is the equivalent of 220mg of zinc sulfate]

“The rationale for my treatment plan is as follows. I combined the data available from China and South Korea with a recent study published from France (cites available on request). We know that hydroxychloroquine helps Zinc enter the cell. We know that Zinc slows viral replication within the cell. Regarding the use of azithromycin, I postulate it prevents secondary bacterial infections. These three drugs are well known and usually well-tolerated, hence the risk to the patient is low.

“Since last Thursday, my team has treated approximately 350 patients in Kiryas Joel and another 150 patients in other areas of New York with the above regimen.

“Of this group and the information provided to me by affiliated medical teams, we have had ZERO deaths, ZERO hospitalizations, and ZERO intubations. In addition, I have not heard of any negative side effects other than approximately 10 percent of patients with temporary nausea and diarrhea.

“In sum, my urgent recommendation is to initiate treatment in the outpatient setting as soon as possible in accordance with the above. Based on my direct experience, it prevents acute respiratory distress syndrome (ARDS), prevents the need for hospitalization and saves lives.”[27]

White House weighing the merits of Dr. Zelenko's protocol for treating coronavirus patients

See: White House weighing the merits of Dr. Zelenko's protocol for treating coronavirus patients

Israeli government and Dr. Zelenko's coronavirus treatment

On March 27, 2020, Zelenko indicated that his protocols were recently on their way to Benjamin Netanyahu (the Prime Minister of Israel).[4]

External links


  1. Dr. Vladimir Zelenko has now treated over 1,450 coronavirus patients (2 deaths) using hydroxychloroquine with 99.99% success rate (latest video interview), Techstartups.com
  2. Multiple references:
  3. WND Staff (March 24, 2020). "Doctor: I treated 350 coronavirus patients with 100% success". WorldNetDaily website.
  4. 4.0 4.1 4.2 "Important update regarding my treatment regimen" (March 27, 2020). YouTube video, 3:05, posted by Dr Vladimir Zelenko M.D.
  5. 5.0 5.1 "My statement to the Israeli health ministry" (March 25, 2020). YouTube video, 4:45, posted by Vladimir Zelenko M.D.
  6. Doctors discover effective, life-saving treatment for Covid-19 By Rev. Mark Peske Our Redeemer Lutheran Church, Grand Rapids Herald-Review, May 30, 2020
  7. Off-Label Drug Use: What You Need to Know
  8. Hydroxychloroquine with zinc among preventative treatments for COVID-19
  9. Is a combo of chloroquine and Zinc a cure for coronavirus?
  10. Is a combo of chloroquine and Zinc a cure for coronavirus?
  11. [https://www.webmd.com/drugs/2/drug-1527-3223/azithromycin-oral/azithromycin-250-500-mg-oral/details Azithromycin Tablet Macrolide Antibiotics
  12. Pfizer reports safety data of azithromycin in Covid-19 trial, clinicaltrialsarena.com
  13. Pfizer reports safety data of azithromycin in Covid-19 trial, clinicaltrialsarena.com
  14. What antibiotics kill Covid-19 (coronavirus)?
  15. Vladimir Zelenko: Important March 27, 2020 update regarding my coronavirus treatment regimen
  16. Dr. Zelenko
  17. Vladimir Zelenko: Important March 27, 2020 update regarding my coronavirus treatment regimen
  18. Dr. Zelenko
  19. My response to Dr Rubin
  20. My response to Dr Rubin
  21. My response to Dr Rubin
  22. Vladimir Zelenko: Important March 27, 2020 update regarding my coronavirus treatment regimen
  23. Dr. Zelenko
  24. Vladimir Zelenko: Important March 27, 2020 update regarding my coronavirus treatment regimen
  25. Dr. Zelenko
  26. Dr. Zelenko
  27. What drugs cured 84 coronavirus patients?, Philippine Star